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NCT00639730 · ClinicalTrials.gov registry record · Phase 1
Use of the Atkins Diet for Children With Sturge Weber Syndrome
A Phase 1 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT00639730: Completed Phase 1 study, sponsored by Johns Hopkins University.
NCT00639730 is a Phase 1 study that has completed, run by Johns Hopkins University. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00639730, a Phase 1 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
This research is being done to find out if the Atkins Diet can be used safely and effectively to reduce seizures in children who have Sturge Weber syndrome. The ketogenic diet is a proven therapy for epilepsy, but can be difficult to use in children. The Atkins Diet is a high fat, high protein, low carbohydrate diet introduced in the 1970s to help with weight loss. It is different from the ketogenic diet in four major ways: no calorie restriction, no fluid restriction, no protein restriction, and is easy to start outside the hospital. People on the Atkins Diet become ketotic (produce high levels of ketones, a certain substance in the body), like patients on the ketogenic diet, and the investigators believe this may lead to seizure control. Children aged 2-18 with Sturge Weber syndrome and seizures at least monthly, who have used at least two anti-seizure drugs may join. 5 children in total will be enrolled.
Primary Outcome
Seizure frequency will be compared to baseline (pre-Diet).
Interventions
- DIETARY_SUPPLEMENT modified Atkins diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2006-05 |
| Est. Completion | 2010-05 |
| Phase | Phase 1 |
What the finished NCT00639730 record still lists
NCT00639730 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which modified Atkins diet is the first listed.
NCT00639730 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00639730 about?
NCT00639730 is a clinical study titled "Use of the Atkins Diet for Children With Sturge Weber Syndrome". This research is being done to find out if the Atkins Diet can be used safely and effectively to reduce seizures in children who have Sturge Weber syndrome. The ketogenic diet is a proven therapy for epilepsy, but can be difficult to use in children. The Atkins Diet is a high fat, high protein, low...
What is the current status of trial NCT00639730?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2006-05. Estimated completion is 2010-05.
What interventions are being tested in trial NCT00639730?
The interventions under investigation include: modified Atkins diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00639730?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00639730's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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