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NCT00639158 · ClinicalTrials.gov registry record · Phase 3

Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood

A Phase 3 study, sponsored by Abbott.

Completed
Registry status
Phase 3
Development phase
543
Enrollment target

NCT00639158: Completed Phase 3 study, sponsored by Abbott.

NCT00639158 is a Phase 3 study that has completed, run by Abbott. The registered enrollment target is 543 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00639158, a Phase 3 study, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 3
Development phase
543 participants
Enrollment target

Study Summary

The primary purpose of this study is to compare the safety and efficacy of ABT-335 (investigational drug) coadministered with atorvastatin and ezetimibe to atorvastatin coadministered with ezetimibe in subjects with abnormal lipid (fat) levels in the blood.

Primary Outcome

\[(Week 12 triglycerides minus baseline triglycerides)/baseline triglycerides\] x 100

Interventions

  • DRUG placebo
  • DRUG atorvastatin
  • DRUG ABT-335
  • DRUG ezetimibe

Trial Details

FieldValue
Enrollment Target 543 participants
Start Date 2008-02
Phase Phase 3
Abbott

181 total trials

What the finished NCT00639158 record still lists

NCT00639158 is an interventional study that assigns participants to a tested intervention. The registered 543 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (30% lower).

The record links to 0 conditions, and to 4 interventions - of which placebo is the first listed.

NCT00639158 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00639158 about?

NCT00639158 is a clinical study titled "Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood". The primary purpose of this study is to compare the safety and efficacy of ABT-335 (investigational drug) coadministered with atorvastatin and ezetimibe to atorvastatin coadministered with ezetimibe in subjects with abnormal lipid (fat) levels in the blood.

What is the current status of trial NCT00639158?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 543 participants. The study started on 2008-02.

What interventions are being tested in trial NCT00639158?

The interventions under investigation include: placebo (DRUG), atorvastatin (DRUG), ABT-335 (DRUG), ezetimibe (DRUG).

Who is sponsoring clinical trial NCT00639158?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00639158's enrollment target sits among peer trials

543 694th of 2000 higher than 1,307 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00639158, the US trial registry maintained by the National Library of Medicine. NCT00639158 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.