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NCT00637481 · ClinicalTrials.gov registry record · Phase 1
A Phase I Prevention Study of Atorvastatin in Women at Increased Risk for Breast Cancer
A Phase 1 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 1
- Development phase
- 66
- Enrollment target
NCT00637481: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).
NCT00637481 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 66 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00637481, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 66 participants
- Enrollment target
Study Summary
Chemoprevention is the use of certain drugs to keep cancer from forming. The use of atorvastatin (Lipitor) may prevent breast cancer. This randomized phase I trial is studying the best dose of atorvastatin in preventing breast cancer in women at increased risk for breast cancer.
Primary Outcome
A single proliferation rate at each time period is calculated for each participant based on the proportion cells expressing KI-67.
Interventions
- OTHER laboratory biomarker analysis
- DRUG atorvastatin calcium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2008-03 |
| Est. Completion | 2012-10 |
| Phase | Phase 1 |
What the finished NCT00637481 record still lists
NCT00637481 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher).
The record links to 0 conditions, and to 2 interventions - of which laboratory biomarker analysis is the first listed.
NCT00637481 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00637481 about?
NCT00637481 is a clinical study titled "A Phase I Prevention Study of Atorvastatin in Women at Increased Risk for Breast Cancer". Chemoprevention is the use of certain drugs to keep cancer from forming. The use of atorvastatin (Lipitor) may prevent breast cancer. This randomized phase I trial is studying the best dose of atorvastatin in preventing breast cancer in women at increased risk for breast cancer.
What is the current status of trial NCT00637481?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2008-03. Estimated completion is 2012-10.
What interventions are being tested in trial NCT00637481?
The interventions under investigation include: laboratory biomarker analysis (OTHER), atorvastatin calcium (DRUG).
Who is sponsoring clinical trial NCT00637481?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00637481's enrollment target sits among peer trials
66 786th of 2000 higher than 1,203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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