Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00634556 · ClinicalTrials.gov registry record · Phase 1

Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)

A Phase 1 study, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 1
Development phase
49
Enrollment target

NCT00634556: Completed Phase 1 study, sponsored by Washington University School of Medicine.

NCT00634556 is a Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 49 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00634556, a Phase 1 study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 1
Development phase
49 participants
Enrollment target

Study Summary

Dr. Kevin J. Black at Washington University is conducting a study to learn whether we can use MRI scans to test dopamine function in the brain and to determine whether the brain performs memory tasks differently in Tourette Syndrome (TS). TS is a movement disorder characterized by vocal tics (sounds) and motor tics (movements). We will measure how and where brain activity changes using magnetic resonance imaging (MRI) scans during memory tasks and after taking levodopa. Levodopa is a drug commonly used for the treatment of Parkinson's disease (PD), a very different movement disorder.

Interventions

  • DRUG placebo
  • DRUG levodopa solution 2mg/ml for i.v. use

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2006-02
Est. Completion 2010-10
Phase Phase 1

What the finished NCT00634556 record still lists

NCT00634556 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT00634556 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00634556 about?

NCT00634556 is a clinical study titled "Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)". Dr. Kevin J. Black at Washington University is conducting a study to learn whether we can use MRI scans to test dopamine function in the brain and to determine whether the brain performs memory tasks differently in Tourette Syndrome (TS). TS is a movement disorder characterized by vocal tics (sounds...

What is the current status of trial NCT00634556?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 49 participants. The study started on 2006-02. Estimated completion is 2010-10.

What interventions are being tested in trial NCT00634556?

The interventions under investigation include: placebo (DRUG), levodopa solution 2mg/ml for i.v. use (DRUG).

Who is sponsoring clinical trial NCT00634556?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00634556's enrollment target sits among peer trials

49 1017th of 2000 higher than 976 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02704858 · 49 participants · Phase 1

    Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

  • NCT03516708 · 49 participants · Phase 1

    Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

  • NCT03692429 · 49 participants · Phase 1

    alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells

  • NCT04329494 · 49 participants · Phase 1

    PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00634556, the US trial registry maintained by the National Library of Medicine. NCT00634556 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.