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NCT00628134 · ClinicalTrials.gov registry record · NA
Self-dispersing Liquids as Aerosol Drug Carriers
A NA study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT00628134: Completed NA study, sponsored by University of Pittsburgh.
NCT00628134 is a NA study that has completed, run by University of Pittsburgh. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00628134, a NA study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
Inhaled medications are often used to treat lung diseases such as cystic fibrosis. We are performing this study to determine whether inhaled medications dissolved in surfactant-based solutions will distribute more evenly throughout the lungs when compared to standard saline-based solutions. We think that inhaling medication that is in a surfactant-based liquid will result in more medication reaching partially blocked parts of the lung. This study will use a special nuclear medicine test called an aerosol deposition scan to compare how a drug spreads in the lung using a surfactant-based aerosol compared to a saline-based aerosol.
Primary Outcome
Measured change in central/peripheral (c/p) dose ratio over a 30 minute period after aersol delivery (c/p at t=30 - c/p at t=0). Central and peripheral lung doses are measured as radioactive counts depicted on nuclear medicine gamma camera images after radioisotope aerosol delivery. The central lung zone is a rectangle with 1/2 the height and 1/2 the width of a box outlining the whole right lung. The peripheral lung zone is defined as the portion of the lung outside of the central lung zone. A c
Interventions
- DRUG calfactant
- DRUG isotonic saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2008-03 |
| Est. Completion | 2009-08 |
| Phase | NA |
What the finished NCT00628134 record still lists
NCT00628134 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which calfactant is the first listed.
NCT00628134 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00628134 about?
NCT00628134 is a clinical study titled "Self-dispersing Liquids as Aerosol Drug Carriers". Inhaled medications are often used to treat lung diseases such as cystic fibrosis. We are performing this study to determine whether inhaled medications dissolved in surfactant-based solutions will distribute more evenly throughout the lungs when compared to standard saline-based solutions. We think...
What is the current status of trial NCT00628134?
This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2008-03. Estimated completion is 2009-08.
What interventions are being tested in trial NCT00628134?
The interventions under investigation include: calfactant (DRUG), isotonic saline (DRUG).
Who is sponsoring clinical trial NCT00628134?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00628134's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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