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NCT00625742 · ClinicalTrials.gov registry record · NA

Multimodal Treatment Strategy for Cancer Cachexia

A NA study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
NA
Development phase
15
Enrollment target

NCT00625742: Clinical Trial NA study, sponsored by M.D. Anderson Cancer Center.

NCT00625742 is a NA study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00625742, a NA study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

The primary aim of this proposal is to present a novel, multimodal treatment strategy for increasing lean body mass in individuals with cancer who experience cachexia between baseline and day 29 (+/- 3 days). The strategy includes graded resistance training and aerobic exercise, targeted nutrient supplementation and pharmacologic intervention (melatonin). We postulate that this strategy, together with the simultaneous management of symptoms that decrease appetite (e.g. depression, pain, and nausea), will also accomplish our secondary objectives of improving clinical outcomes such as strength and function between baseline and day 29 (+/- 3 days).

Primary Outcome

Measure increases in lean body mass in individuals with cancer who experience cachexia between baseline and day 29 (+/- 3 days).

Interventions

  • BEHAVIORAL Aerobic Exercise
  • DRUG Atenolol
  • DRUG Melatonin
  • DIETARY_SUPPLEMENT Juven
  • BEHAVIORAL Graded Resistance Training

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2008-02
Est. Completion 2014-06
Phase NA
M.D. Anderson Cancer Center

2,692 total trials

Why NCT00625742 stopped before completion

NCT00625742 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 5 interventions - of which Aerobic Exercise is the first listed.

NCT00625742 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00625742 about?

NCT00625742 is a clinical study titled "Multimodal Treatment Strategy for Cancer Cachexia". The primary aim of this proposal is to present a novel, multimodal treatment strategy for increasing lean body mass in individuals with cancer who experience cachexia between baseline and day 29 (+/- 3 days). The strategy includes graded resistance training and aerobic exercise, targeted nutrient su...

What is the current status of trial NCT00625742?

This trial is currently terminated. It is a NA study. The enrollment target is 15 participants. The study started on 2008-02. Estimated completion is 2014-06.

What interventions are being tested in trial NCT00625742?

The interventions under investigation include: Aerobic Exercise (BEHAVIORAL), Atenolol (DRUG), Melatonin (DRUG), Juven (DIETARY_SUPPLEMENT), Graded Resistance Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT00625742?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00625742's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00625742, the US trial registry maintained by the National Library of Medicine. NCT00625742 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.