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NCT00617955 · ClinicalTrials.gov registry record
Effects of Aprotinin During Cardiac Surgery/Long Term Death Rates
A clinical trial, sponsored by State University of New York - Upstate Medical University.
- Completed
- Registry status
- 462
- Enrollment target
NCT00617955 is a clinical trial that has completed, run by State University of New York - Upstate Medical University. The registered enrollment target is 462 participants.
The verdict
NCT00617955 has completed, sponsored by State University of New York - Upstate Medical University.
- COMPLETED
- Registry status
- 462 participants
- Enrollment target
Study Summary
The dept. of Anesthesiology currently has a database of subjects whom had surgery and received either Aprotinin or Amicar in the OR. The current viewpoint is that Aprotinin is more harmful than Amicard. In an effort to see what the long term outcomes were for subjects whom had surgery here at Upstate, it was decided to look at long term death rates to see if any differences. A student t-test will be used to determine statistical significance where a p value of \<0.05 will be deemed significant. Using data from 462 subjects that had undergone cardiac surgery at SUNY Upstate Medical University, CABG only and the long term mortality rate from the Mangano, et.al. publications, the unadjusted mortality for the two drugs are Aprotinin 5.4% and Amicar 1.2%. A power analysis was performed using the hospital mortality rates of 5.4% and 1.2% with the sample size in the propensity data and a p-value of 0.05. The result was a power of 81.7%.
Interventions
- DRUG Aprotinin
- DRUG Amicar
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 462 participants |
| Start Date | 2007-09 |
| Est. Completion | 2009-06 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00617955
The ClinicalTrials.gov registry entry for NCT00617955 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 462 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is State University of New York - Upstate Medical University, which has 113 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Aprotinin is the first listed.
NCT00617955 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00617955 about?
NCT00617955 is a clinical study titled "Effects of Aprotinin During Cardiac Surgery/Long Term Death Rates". The dept. of Anesthesiology currently has a database of subjects whom had surgery and received either Aprotinin or Amicar in the OR. The current viewpoint is that Aprotinin is more harmful than Amicard. In an effort to see what the long term outcomes were for subjects whom had surgery here at Upstat...
What is the current status of trial NCT00617955?
This trial is currently completed. The enrollment target is 462 participants. The study started on 2007-09. Estimated completion is 2009-06.
What interventions are being tested in trial NCT00617955?
The interventions under investigation include: Aprotinin (DRUG), Amicar (DRUG).
Who is sponsoring clinical trial NCT00617955?
This trial is sponsored by State University of New York - Upstate Medical University, which has 113 total clinical trials registered on ClinicalTrials.gov.
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