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NCT00616759 · ClinicalTrials.gov registry record · NA

The Effect on Cognition of Terminating ECT Induced Seizures With Propofol

A NA study, sponsored by Loma Linda University.

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT00616759: Completed NA study, sponsored by Loma Linda University.

NCT00616759 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00616759, a NA study, has completed, sponsored by Loma Linda University.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

Participating subjects are those who are referred for electroconvulsive therapy (ECT) for severe depression who have agreed to the protocol. The control group receives ECT as usual. The other group receives propofol to terminate the ECT-induced seizure timed so that the seizure lasts at least 25 seconds. Extensive neuropsychological testing is being done on both groups before beginning ECT and within 48 hours after the 6th treatment. Multiple markers of the rapidity of recovery from anesthesia are being obtained from all subjects for 6 ECTs.

Primary Outcome

WMS-III Auditory Delayed Index is a measure of memory functioning. The results given are the post-ECT testing results. A smaller number indicates less memory disturbance on this scale. The range of scores is between 0-140 with higher scores indicating better memory function.

Interventions

  • DRUG propofol
  • PROCEDURE electroconvulsive therapy
  • PROCEDURE electroconvulsive therapy plus propofol

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2006-09
Est. Completion 2010-03-24
Phase NA
Loma Linda University

237 total trials

What the finished NCT00616759 record still lists

NCT00616759 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which propofol is the first listed.

NCT00616759 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00616759 about?

NCT00616759 is a clinical study titled "The Effect on Cognition of Terminating ECT Induced Seizures With Propofol". Participating subjects are those who are referred for electroconvulsive therapy (ECT) for severe depression who have agreed to the protocol. The control group receives ECT as usual. The other group receives propofol to terminate the ECT-induced seizure timed so that the seizure lasts at least 25 sec...

What is the current status of trial NCT00616759?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2006-09. Estimated completion is 2010-03-24.

What interventions are being tested in trial NCT00616759?

The interventions under investigation include: propofol (DRUG), electroconvulsive therapy (PROCEDURE), electroconvulsive therapy plus propofol (PROCEDURE).

Who is sponsoring clinical trial NCT00616759?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00616759's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00616759, the US trial registry maintained by the National Library of Medicine. NCT00616759 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.