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NCT00616603 · ClinicalTrials.gov registry record · NA
The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks
A NA study, sponsored by Loma Linda University.
- Terminated
- Registry status
- NA
- Development phase
- 43
- Enrollment target
NCT00616603: Clinical Trial NA study, sponsored by Loma Linda University.
NCT00616603 is a NA study that was terminated before completion, run by Loma Linda University. The registered enrollment target is 43 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00616603, a NA study, was terminated before completion, sponsored by Loma Linda University.
- TERMINATED
- Registry status
- NA
- Development phase
- 43 participants
- Enrollment target
Study Summary
Dexamethasone is a commonly used steroid. This medication has been used for many years by physicians for many different indications. Recent articles, multiple case reports, and experience at this institution have indicated that dexamethasone successfully prolongs the effective duration of local anesthetics for regional blocks. This can cause a significant reduction in postoperative pain and the decreased need for postoperative narcotics. Although other adjuncts can be used for prolonging nerve blocks, epinephrine causes local vasoconstriction which can cause ischemia and nerve damage in a large nerve such as the sciatic nerve.Dexamethasone will not cause this problem and yet could prolong the duration of a sciatic nerve block. Therefore, the goal of this study is to prospectively evaluate the effectiveness of dexamethasone, both locally through the nerve block and systemically via IV administration, in prolonging the effective duration of local anesthetics when used in sciatic nerve blocks.
Primary Outcome
Intraoperative opioid requirement PACU opioid requirement Floor opioid usage Time of onset of motor block (or weakness) Time of onset of sensory block Return of motor function Return of sensation Pain scores
Interventions
- DRUG Dexamethasone
- DRUG Normal Saline
- DRUG Ropivacaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2007-08 |
| Est. Completion | 2011-05 |
| Phase | NA |
Why NCT00616603 stopped before completion
NCT00616603 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 3 interventions - of which Dexamethasone is the first listed.
NCT00616603 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00616603 about?
NCT00616603 is a clinical study titled "The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks". Dexamethasone is a commonly used steroid. This medication has been used for many years by physicians for many different indications. Recent articles, multiple case reports, and experience at this institution have indicated that dexamethasone successfully prolongs the effective duration of local anes...
What is the current status of trial NCT00616603?
This trial is currently terminated. It is a NA study. The enrollment target is 43 participants. The study started on 2007-08. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00616603?
The interventions under investigation include: Dexamethasone (DRUG), Normal Saline (DRUG), Ropivacaine (DRUG).
Who is sponsoring clinical trial NCT00616603?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00616603's enrollment target sits among peer trials
43 1435th of 2000 higher than 565 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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