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NCT00615472 · ClinicalTrials.gov registry record · NA

Intravenous Versus Inhalational Anesthesia in Parkinson's Disease

A NA study, sponsored by Columbia University.

Terminated
Registry status
NA
Development phase
58
Enrollment target

NCT00615472 is a NA study that was terminated before completion, run by Columbia University. The registered enrollment target is 58 participants.

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The verdict

NCT00615472, a NA study, was terminated before completion, sponsored by Columbia University.

TERMINATED
Registry status
NA
Development phase
58 participants
Enrollment target

Study Summary

Parkinson's disease is a common progressive degenerative disease affecting 3% of all patients over the age of 65. Given their age and frailty, these patients frequently require surgical procedures with general anesthesia. However, after surgery, patients with Parkinson's disease have longer hospital stays and a greater chance of not returning to independent living compared to age-matched controls (Berman MF, unpublished data). In part, this is due to a higher rate of post-operative delirium, which had an incidence of 60% in this population in one study. There is anecdotal evidence from neurologists specializing in movement disorder suggesting that there is also significant deterioration in parkinsonian motor symptoms and cognition lasting for months or years following surgery and anesthesia. The basis for this deterioration is unknown. We hypothesize that these problems are caused by particular medications used during inhaled anesthesia for surgical procedures.

Interventions

  • DRUG Propofol
  • DRUG Isoflurane
  • DRUG Remifentanil

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2003-10
Est. Completion 2011-04
Phase NA

Sponsor

Columbia University

958 total trials

What the Registry Record Tells You About NCT00615472

The ClinicalTrials.gov registry entry for NCT00615472 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Propofol is the first listed.

NCT00615472 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00615472 about?

NCT00615472 is a clinical study titled "Intravenous Versus Inhalational Anesthesia in Parkinson's Disease". Parkinson's disease is a common progressive degenerative disease affecting 3% of all patients over the age of 65. Given their age and frailty, these patients frequently require surgical procedures with general anesthesia. However, after surgery, patients with Parkinson's disease have longer hospital...

What is the current status of trial NCT00615472?

This trial is currently terminated. It is a NA study. The enrollment target is 58 participants. The study started on 2003-10. Estimated completion is 2011-04.

What interventions are being tested in trial NCT00615472?

The interventions under investigation include: Propofol (DRUG), Isoflurane (DRUG), Remifentanil (DRUG).

Who is sponsoring clinical trial NCT00615472?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.