Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00611403 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients

A Phase 2 study, sponsored by Allergan.

Completed
Registry status
Phase 2
Development phase
137
Enrollment target

NCT00611403: Completed Phase 2 study, sponsored by Allergan.

NCT00611403 is a Phase 2 study that has completed, run by Allergan. The registered enrollment target is 137 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00611403, a Phase 2 study, has completed, sponsored by Allergan.

COMPLETED
Registry status
Phase 2
Development phase
137 participants
Enrollment target

Study Summary

This study will evaluate the safety and efficacy of cyclosporine ophthalmic emulsion administered twice daily following LASIK surgery

Primary Outcome

Percentage of patients with clinical success at month 6. Clinical success is defined as the percentage of patients with corneal sensitivity (the capability of the cornea to respond to stimulation) \>= 50 millimeters in all regions of the study eye at month 6 of the Treatment Phase.

Interventions

  • DRUG Cyclosporine Ophthalmic Emulsion 0.05% (RESTASIS®)
  • DRUG Artificial Tears REFRESH ENDURA®

Trial Details

FieldValue
Enrollment Target 137 participants
Start Date 2007-12
Est. Completion 2009-06
Phase Phase 2
Allergan

314 total trials

What the finished NCT00611403 record still lists

NCT00611403 is an interventional study that assigns participants to a tested intervention. The registered 137 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.

The record links to 0 conditions, and to 2 interventions - of which Cyclosporine Ophthalmic Emulsion 0.05% (RESTASIS®) is the first listed.

NCT00611403 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00611403 about?

NCT00611403 is a clinical study titled "Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients". This study will evaluate the safety and efficacy of cyclosporine ophthalmic emulsion administered twice daily following LASIK surgery

What is the current status of trial NCT00611403?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 137 participants. The study started on 2007-12. Estimated completion is 2009-06.

What interventions are being tested in trial NCT00611403?

The interventions under investigation include: Cyclosporine Ophthalmic Emulsion 0.05% (RESTASIS®) (DRUG), Artificial Tears REFRESH ENDURA® (DRUG).

Who is sponsoring clinical trial NCT00611403?

This trial is sponsored by Allergan, which has 314 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00611403's enrollment target sits among peer trials

137 527th of 2000 higher than 1,474 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05091424 · 137 participants · Phase 1

    A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

  • NCT05655182 · 137 participants · Phase 1

    A Study of BLB-201 RSV Vaccine in Infants and Children

  • NCT06571669 · 137 participants · NA

    BOOM-IBD2 Pivotal Clinical Trial

  • NCT06644768 · 137 participants · Phase 1

    A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00611403, the US trial registry maintained by the National Library of Medicine. NCT00611403 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.