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NCT00608582 · ClinicalTrials.gov registry record · Phase 1

Transcranial Magnetic Stimulation to Improve Speech in Aphasia

A Phase 1 study, sponsored by Boston University.

Completed
Registry status
Phase 1
Development phase
63
Enrollment target

NCT00608582: Completed Phase 1 study, sponsored by Boston University.

NCT00608582 is a Phase 1 study that has completed, run by Boston University. The registered enrollment target is 63 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00608582, a Phase 1 study, has completed, sponsored by Boston University.

COMPLETED
Registry status
Phase 1
Development phase
63 participants
Enrollment target

Study Summary

The purpose of this study is to examine whether repetitive transcranial magnetic stimulation (rTMS) can be used to improve speech in chronic stroke patients with aphasia. Aphasia patients can have problems with speech production. The rTMS procedure allows painless, noninvasive stimulation of human cortex from outside the head. Chronic aphasia patients have been observed in our functional magnetic resonance brain imaging studies to have excess brain activation in brain areas possibly related to language on the right side of the brain (opposite side to where the stroke took place). It is expected that suppression of activity in the directly targeted brain region will have an overall modulating effect on the neural network for naming (and propositional speech) and will result in behavioral improvement.

Primary Outcome

Pictures named correctly on Boston Naming Test (BNT), First 20 Pictures

Interventions

  • DEVICE Transcranial Magnetic Stimulation, Repetitive

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 2002-07
Est. Completion 2013-06
Phase Phase 1
Boston University

185 total trials

What the finished NCT00608582 record still lists

NCT00608582 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 63 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which Transcranial Magnetic Stimulation, Repetitive is the first listed.

NCT00608582 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00608582 about?

NCT00608582 is a clinical study titled "Transcranial Magnetic Stimulation to Improve Speech in Aphasia". The purpose of this study is to examine whether repetitive transcranial magnetic stimulation (rTMS) can be used to improve speech in chronic stroke patients with aphasia. Aphasia patients can have problems with speech production. The rTMS procedure allows painless, noninvasive stimulation of human c...

What is the current status of trial NCT00608582?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 63 participants. The study started on 2002-07. Estimated completion is 2013-06.

What interventions are being tested in trial NCT00608582?

The interventions under investigation include: Transcranial Magnetic Stimulation, Repetitive (DEVICE).

Who is sponsoring clinical trial NCT00608582?

This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00608582's enrollment target sits among peer trials

63 820th of 2000 higher than 1,177 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00608582, the US trial registry maintained by the National Library of Medicine. NCT00608582 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.