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NCT00603720 · ClinicalTrials.gov registry record · NA
Role of Nitric Oxide in the Impact of Aging on Myocardial Remodeling
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT00603720: Completed NA study, sponsored by Washington University School of Medicine.
NCT00603720 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 54 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00603720, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
The purpose of this study is to determine, with Positron Emission Tomography (PET), the role of nitric oxide in the age-associated effect on fatty acid and glucose delivery on myocardial substrate metabolism.
Primary Outcome
Determine in young healthy volunteers the extent to which acute inhibition of nitric oxide production will effect a shift in myocardial substrate utilization characterized as a decline in myocardial fatty acid oxidation, and perhaps myocardial fatty acid utilization, and increase in myocardial glucose uptake, and whether these changes are associated with a decline in LV function.
Interventions
- DRUG L-Arginine
- DRUG L-NAME
- DRUG Phenylephrine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2005-09 |
| Est. Completion | 2008-06 |
| Phase | NA |
What the finished NCT00603720 record still lists
NCT00603720 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 3 interventions - of which L-Arginine is the first listed.
NCT00603720 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00603720 about?
NCT00603720 is a clinical study titled "Role of Nitric Oxide in the Impact of Aging on Myocardial Remodeling". The purpose of this study is to determine, with Positron Emission Tomography (PET), the role of nitric oxide in the age-associated effect on fatty acid and glucose delivery on myocardial substrate metabolism.
What is the current status of trial NCT00603720?
This trial is currently completed. It is a NA study. The enrollment target is 54 participants. The study started on 2005-09. Estimated completion is 2008-06.
What interventions are being tested in trial NCT00603720?
The interventions under investigation include: L-Arginine (DRUG), L-NAME (DRUG), Phenylephrine (DRUG).
Who is sponsoring clinical trial NCT00603720?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00603720's enrollment target sits among peer trials
54 1268th of 2000 higher than 730 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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