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NCT00602225 · ClinicalTrials.gov registry record · Phase 1

Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

A Phase 1 study, sponsored by University of Washington.

Completed
Registry status
Phase 1
Development phase
50
Enrollment target

NCT00602225: Completed Phase 1 study, sponsored by University of Washington.

NCT00602225 is a Phase 1 study that has completed, run by University of Washington. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00602225, a Phase 1 study, has completed, sponsored by University of Washington.

COMPLETED
Registry status
Phase 1
Development phase
50 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as clofarabine and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or stopping them from dividing. Colony stimulating factors, such as G-CSF, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy. PURPOSE: This phase I trial is studying the side effects and best dose of clofarabine to see how well it works when given together with cytarabine and G-CSF in treating patients with relapsed or refractory acute myeloid leukemia

Interventions

  • DRUG clofarabine
  • BIOLOGICAL filgrastim
  • DRUG cytarabine

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2007-12
Est. Completion 2015-04
Phase Phase 1
University of Washington

1,048 total trials

What the finished NCT00602225 record still lists

NCT00602225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).

The record links to 0 conditions, and to 3 interventions - of which clofarabine is the first listed.

NCT00602225 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00602225 about?

NCT00602225 is a clinical study titled "Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia". RATIONALE: Drugs used in chemotherapy, such as clofarabine and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or stopping them from dividing. Colony stimulating factors, such as G-CSF, may increase the number of immune cells found in bone marrow or...

What is the current status of trial NCT00602225?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2007-12. Estimated completion is 2015-04.

What interventions are being tested in trial NCT00602225?

The interventions under investigation include: clofarabine (DRUG), filgrastim (BIOLOGICAL), cytarabine (DRUG).

Who is sponsoring clinical trial NCT00602225?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00602225's enrollment target sits among peer trials

50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00602225, the US trial registry maintained by the National Library of Medicine. NCT00602225 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.