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NCT00595478 · ClinicalTrials.gov registry record · NA
Family Based Contingency Management for Adolescent Alcohol Abuse
A NA study, sponsored by Dartmouth-Hitchcock Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
NCT00595478: Completed NA study, sponsored by Dartmouth-Hitchcock Medical Center.
NCT00595478 is a NA study that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 75 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00595478, a NA study, has completed, sponsored by Dartmouth-Hitchcock Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
Study Summary
The goal is to adapt the family-based CM treatment to target primary adolescent alcohol abuse and dependence. Specific Aim 1 is to provide a preliminary demonstration of the efficacy of a family-based CM intervention to treat adolescent alcohol abuse and dependence. CM components include: 1. an incentive program to enhance the adolescent's engagement in the treatment process and engender alcohol abstinence by providing positive reinforcement for documented abstinence via breathalyzers administered by parents regularly at home, self and parent report, and clinic-based urine drug testing; and 2. a parent management training program to enhance and maintain the positive effects of the incentive program by teaching parents how to effectively use contingency management in the home environment to motivate their adolescent to achieve abstinence and improve their behavior in other domains. A randomized trial will determine whether the CM intervention enhances outcomes when added to a standard individual cognitive behavioral therapy (CBT). Specific Aim 2 is to determine whether and how treatment interventions modify parental and adolescent risk and protective factors using observational and laboratory measures (parenting practices, family functioning, risk taking, delay discounting, and child and parent psychopathology) and to determine whether these factors are associated with outcomes over time. Specific Aim 3 is to test gene x environment (treatment) interactions in adolescent substance abuse. Findings will extend the scientific evidence for CM and support the ability of parents to implement CM at home. Findings that support the CM model's efficacy will make a significant contribution to research on the treatment of adolescent alcohol abuse, which has lagged behind research on adult substance abuse and on adolescent illicit drug use.
Primary Outcome
Number of non-abstinent urinalysis (ETG-positive) samples during 14 weeks of treatment (considering missing samples as non-abstinent)
Interventions
- BEHAVIORAL Motivational Enhancement Therapy (MET)/CBT+CM
- BEHAVIORAL Motivational Enhancement Therapy (MET)/CBT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2007-08 |
| Est. Completion | 2014-05 |
| Phase | NA |
What the finished NCT00595478 record still lists
NCT00595478 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Motivational Enhancement Therapy (MET)/CBT+CM is the first listed.
NCT00595478 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00595478 about?
NCT00595478 is a clinical study titled "Family Based Contingency Management for Adolescent Alcohol Abuse". The goal is to adapt the family-based CM treatment to target primary adolescent alcohol abuse and dependence. Specific Aim 1 is to provide a preliminary demonstration of the efficacy of a family-based CM intervention to treat adolescent alcohol abuse and dependence. CM components include: 1. an in...
What is the current status of trial NCT00595478?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2007-08. Estimated completion is 2014-05.
What interventions are being tested in trial NCT00595478?
The interventions under investigation include: Motivational Enhancement Therapy (MET)/CBT+CM (BEHAVIORAL), Motivational Enhancement Therapy (MET)/CBT (BEHAVIORAL).
Who is sponsoring clinical trial NCT00595478?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00595478's enrollment target sits among peer trials
75 1069th of 2000 higher than 919 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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