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NCT00594152 · ClinicalTrials.gov registry record · Phase 3
Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT)
A Phase 3 study, sponsored by Joslin Diabetes Center.
- Completed
- Registry status
- Phase 3
- Development phase
- 71
- Enrollment target
NCT00594152: Completed Phase 3 study, sponsored by Joslin Diabetes Center.
NCT00594152 is a Phase 3 study that has completed, run by Joslin Diabetes Center. The registered enrollment target is 71 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00594152, a Phase 3 study, has completed, sponsored by Joslin Diabetes Center.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 71 participants
- Enrollment target
Study Summary
Investigators with the goal of optimizing glycemic and blood pressure control saw type 1 diabetic patients weekly. A control group received 3-4 subcutaneous insulin injections per day; an intravenous insulin pulsed infusion group received, in addition, three one hour infusions in a pulsatile fashion over one eight hour period each week. Patients were followed for 12 months with periodic testing of renal function by repeated blood and urinary analyses; diabetes control by blood testing and diabetes impact measurement score; cardiac and autonomic function by echocardiography, 24 hour electrocardiographic testing; and visual changes with repeated fundus photography. The study hypothesis was that correction of respiratory quotient would correct the defect leading to microvascular complications of diabetes (Type 1).
Interventions
- DRUG CIIIT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 71 participants |
| Start Date | 1993-01 |
| Est. Completion | 1995-01 |
| Phase | Phase 3 |
What the finished NCT00594152 record still lists
NCT00594152 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 71 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which CIIIT is the first listed.
NCT00594152 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00594152 about?
NCT00594152 is a clinical study titled "Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT)". Investigators with the goal of optimizing glycemic and blood pressure control saw type 1 diabetic patients weekly. A control group received 3-4 subcutaneous insulin injections per day; an intravenous insulin pulsed infusion group received, in addition, three one hour infusions in a pulsatile fashion...
What is the current status of trial NCT00594152?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 71 participants. The study started on 1993-01. Estimated completion is 1995-01.
What interventions are being tested in trial NCT00594152?
The interventions under investigation include: CIIIT (DRUG).
Who is sponsoring clinical trial NCT00594152?
This trial is sponsored by Joslin Diabetes Center, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00594152's enrollment target sits among peer trials
71 1784th of 2000 higher than 216 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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