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NCT00592280 · ClinicalTrials.gov registry record · Early Phase 1
Two-Layer Method Preservation and Resuscitation of the Cadaveric Pancreas Before Transplantation
A Early Phase 1 study, sponsored by University of Nebraska.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT00592280: Clinical Trial Early Phase 1 study, sponsored by University of Nebraska.
NCT00592280 is a Early Phase 1 study that was terminated before completion, run by University of Nebraska. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00592280, a Early Phase 1 study, was terminated before completion, sponsored by University of Nebraska.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
The purpose of this project is to compare the effect of oxygenated preservation of the pancreas before transplantation using the "Two-Layer Method" (TLM) against outcomes previously experienced with organs preserved using only standard University of Wisconsin (UW) storage solution. It is our hypothesis that TLM preservation will reduce the frequency and severity of complications of pancreas transplantation, increase the number of organs acceptable for transplantation, and spare individual patients and their families suffering and hardship.
Primary Outcome
Post-transplantation adverse event frequency (graft thrombosis, hemorrhage, peri-pancreatic abscess, re-laparotomy, cadaver duodenum leak, pseudo-aneurysm formation, rejection, graft failure, patient death)
Interventions
- DRUG Two-Layer Method pancreas preservation system drug
- DEVICE Two-Layer Method pancreas preservation system device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2007-10 |
| Est. Completion | 2009-04 |
| Phase | Early Phase 1 |
Why NCT00592280 stopped before completion
NCT00592280 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Two-Layer Method pancreas preservation system drug is the first listed.
NCT00592280 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00592280 about?
NCT00592280 is a clinical study titled "Two-Layer Method Preservation and Resuscitation of the Cadaveric Pancreas Before Transplantation". The purpose of this project is to compare the effect of oxygenated preservation of the pancreas before transplantation using the "Two-Layer Method" (TLM) against outcomes previously experienced with organs preserved using only standard University of Wisconsin (UW) storage solution. It is our hypothe...
What is the current status of trial NCT00592280?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2007-10. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00592280?
The interventions under investigation include: Two-Layer Method pancreas preservation system drug (DRUG), Two-Layer Method pancreas preservation system device (DEVICE).
Who is sponsoring clinical trial NCT00592280?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00592280's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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