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NCT00591305 · ClinicalTrials.gov registry record · NA
New Therapy of Laryngeal Papilloma In Children
A NA study, sponsored by Boston University.
- Terminated
- Registry status
- NA
- Development phase
- 1
- Enrollment target
NCT00591305: Clinical Trial NA study, sponsored by Boston University.
NCT00591305 is a NA study that was terminated before completion, run by Boston University. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00591305, a NA study, was terminated before completion, sponsored by Boston University.
- TERMINATED
- Registry status
- NA
- Development phase
- 1 participants
- Enrollment target
Study Summary
This study will determine efficacy of a new and combined treatment of laryngeal recurrent respiratory papillomatosis (RRP), by using a 585 nm pulsed dye laser (PDL) and a dietary supplement, diindolylmethane (DIM). We will compare this new treatment with PDL-only, in a total of 30 children (15 of each treatment), to determine whether this combined treatment would be effective and safe in preventing the RRP recurrence. This is the first study to combine PDL technique with DIM, to develop a new, voice-preserving and long-term effective method of managing laryngeal RRP in children.
Primary Outcome
vocal lesion size and area after 5 month with surgery visible lesion found in \>50% of the treated tissue area, after surgery
Interventions
- DIETARY_SUPPLEMENT diindolylmethane (DIM)
- DEVICE 585 nm pulsed dye laser
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2007-09 |
| Est. Completion | 2011-10 |
| Phase | NA |
Why NCT00591305 stopped before completion
NCT00591305 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which diindolylmethane (DIM) is the first listed.
NCT00591305 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00591305 about?
NCT00591305 is a clinical study titled "New Therapy of Laryngeal Papilloma In Children". This study will determine efficacy of a new and combined treatment of laryngeal recurrent respiratory papillomatosis (RRP), by using a 585 nm pulsed dye laser (PDL) and a dietary supplement, diindolylmethane (DIM). We will compare this new treatment with PDL-only, in a total of 30 children (15 of ea...
What is the current status of trial NCT00591305?
This trial is currently terminated. It is a NA study. The enrollment target is 1 participants. The study started on 2007-09. Estimated completion is 2011-10.
What interventions are being tested in trial NCT00591305?
The interventions under investigation include: diindolylmethane (DIM) (DIETARY_SUPPLEMENT), 585 nm pulsed dye laser (DEVICE).
Who is sponsoring clinical trial NCT00591305?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00591305's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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