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NCT00591123 · ClinicalTrials.gov registry record · Phase 2

Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia

A Phase 2 study of Unresectable Adenocarcinoma of the Esophagus and Metastatic Adenocarcinoma of the Esophagus, sponsored by Translational Oncology Research International.

Completed
Registry status
Phase 2
Development phase
38
Enrollment target
2
Study locations

NCT00591123 is a Phase 2 study of Unresectable Adenocarcinoma of the Esophagus and Metastatic Adenocarcinoma of the Esophagus that has completed, run by Translational Oncology Research International. The registered enrollment target is 38 participants. The trial reports 2 study locations across 1 state.

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The verdict

NCT00591123, a Phase 2 study of Unresectable Adenocarcinoma of the Esophagus and Metastatic Adenocarcinoma of the Esophagus, has completed, sponsored by Translational Oncology Research International.

COMPLETED
Registry status
Phase 2
Development phase
38 participants
Enrollment target
2
Study locations

Study Summary

In this study, Erlotinib and 5-Fluorouracil (5-FU), Leucovorin and Oxaliplatin (a regimen known also as FOLFOX-6) will be the chemotherapy study drugs. The main purpose of this study is to test the safety and effectiveness of this combination of chemotherapy drugs and to see how they affect your cancer. Another purpose of this study is to examine samples from your blood and tumor. This research will be done to better understand how subjects respond to treatment. Specifically, researchers will look at the way your genes and proteins respond to drugs like those used in this study.

Interventions

  • DRUG 5-FU
  • DRUG FOLFOX
  • DRUG Erlotinib

Study Locations (2)

California

  • Translational Oncology Research International (TORI) Network - Los Angeles
  • UCLA Jonsson Comprehensive Cancer Center - Los Angeles

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2007-12
Est. Completion 2015-09
Phase Phase 2

What the Registry Record Tells You About NCT00591123

The ClinicalTrials.gov registry entry for NCT00591123 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Translational Oncology Research International, which has 11 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Unresectable Adenocarcinoma of the Esophagus appearing as the primary indexed condition, and to 3 interventions - of which 5-FU is the first listed.

NCT00591123 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00591123 about?

NCT00591123 is a clinical study titled "Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia". In this study, Erlotinib and 5-Fluorouracil (5-FU), Leucovorin and Oxaliplatin (a regimen known also as FOLFOX-6) will be the chemotherapy study drugs. The main purpose of this study is to test the safety and effectiveness of this combination of chemotherapy drugs and to see how they affect your can...

What is the current status of trial NCT00591123?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 38 participants. The study started on 2007-12. Estimated completion is 2015-09.

What conditions does trial NCT00591123 study?

This clinical trial studies the following conditions: Unresectable Adenocarcinoma of the Esophagus, Metastatic Adenocarcinoma of the Esophagus, Unresectable Adenocarcinoma of Gastric Cardia, Metastatic Adenocarcinoma of Gastric Cardia.

What interventions are being tested in trial NCT00591123?

The interventions under investigation include: 5-FU (DRUG), FOLFOX (DRUG), Erlotinib (DRUG).

Who is sponsoring clinical trial NCT00591123?

This trial is sponsored by Translational Oncology Research International, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00591123 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.