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NCT00590954 · ClinicalTrials.gov registry record · Phase 2

Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas

A Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 2
Development phase
32
Enrollment target

NCT00590954: Completed Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

NCT00590954 is a Phase 2 study that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 32 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (76% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00590954, a Phase 2 study, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
32 participants
Enrollment target

Study Summary

The purpose of this study is to test the effectiveness of perifosine in preventing further tumor growth using the established optimal dose of the drug. A second goal is to determine if perifosine can block the molecules in the tumor that drive it to divide and grow.

Interventions

  • DRUG Perifosine

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2006-05
Est. Completion 2019-11-11
Phase Phase 2
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT00590954 record still lists

NCT00590954 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (76% lower).

The record links to 0 conditions, and to 1 intervention - of which Perifosine is the first listed.

NCT00590954 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00590954 about?

NCT00590954 is a clinical study titled "Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas". The purpose of this study is to test the effectiveness of perifosine in preventing further tumor growth using the established optimal dose of the drug. A second goal is to determine if perifosine can block the molecules in the tumor that drive it to divide and grow.

What is the current status of trial NCT00590954?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2006-05. Estimated completion is 2019-11-11.

What interventions are being tested in trial NCT00590954?

The interventions under investigation include: Perifosine (DRUG).

Who is sponsoring clinical trial NCT00590954?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00590954's enrollment target sits among peer trials

32 1563rd of 2000 higher than 423 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00590954, the US trial registry maintained by the National Library of Medicine. NCT00590954 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.