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NCT00585260 · ClinicalTrials.gov registry record · Early Phase 1

Mannitol Bronchoprovocation Challenge Ancillary Study/ACRN

A Early Phase 1 study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
Early Phase 1
Development phase
66
Enrollment target

NCT00585260: Completed Early Phase 1 study, sponsored by University of Wisconsin, Madison.

NCT00585260 is a Early Phase 1 study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 66 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (25% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00585260, a Early Phase 1 study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
Early Phase 1
Development phase
66 participants
Enrollment target

Study Summary

This is an ancillary study conducted as part of the BASALT trial \[NCT00495157\]. The overall hypotheses are: 1) an indirect airway challenge procedure using mannitol can safely characterize asthma phenotypes, predict asthma control and exacerbations, predict responses to interventions, and perform more specifically than a direct methacholine challenge and; 2) PX27 pore function in whole blood correlates with measures of airway hyperresponsiveness induced by methacholine and/or mannitol challenges

Primary Outcome

Mannitol bronchoprovocation challenge testing is safe, effective and well tolerated as compared to methacholine (conducted as part of the main BASALT trial).

Interventions

  • DRUG mannitol

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2007-12
Est. Completion 2010-02-16
Phase Early Phase 1
University of Wisconsin, Madison

1,039 total trials

What the finished NCT00585260 record still lists

NCT00585260 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (25% higher).

The record links to 0 conditions, and to 1 intervention - of which mannitol is the first listed.

NCT00585260 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00585260 about?

NCT00585260 is a clinical study titled "Mannitol Bronchoprovocation Challenge Ancillary Study/ACRN". This is an ancillary study conducted as part of the BASALT trial \[NCT00495157\]. The overall hypotheses are: 1) an indirect airway challenge procedure using mannitol can safely characterize asthma phenotypes, predict asthma control and exacerbations, predict responses to interventions, and perform...

What is the current status of trial NCT00585260?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 66 participants. The study started on 2007-12. Estimated completion is 2010-02-16.

What interventions are being tested in trial NCT00585260?

The interventions under investigation include: mannitol (DRUG).

Who is sponsoring clinical trial NCT00585260?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00585260's enrollment target sits among peer trials

66 363rd of 2000 higher than 1,630 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00585260, the US trial registry maintained by the National Library of Medicine. NCT00585260 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.