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NCT00581048 · ClinicalTrials.gov registry record · NA
Study on the Role of Treatment With Vitamin E on Asthmatic Responses in Allergic Asthmatics
A NA study, sponsored by Vanderbilt University.
- Completed
- Registry status
- NA
- Development phase
- 33
- Enrollment target
NCT00581048 is a NA study that has completed, run by Vanderbilt University. The registered enrollment target is 33 participants.
The verdict
NCT00581048, a NA study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
Study Summary
Asthma is a common respiratory disease of unknown etiology which currently affects approximately 7.5 % of the adult population ( ). Asthma is an inflammatory disorder of the airways. Airway inflammation is evident not only in patients with fatal asthma but also in mild asthmatics ( ). Oxidant stress, defined as inadequately controlled generation of toxic reactive oxygen species (ROS) in the cells or tissues is a common feature of inflammation, and has also been documented in asthma ( , ). However, the current understanding of the relationship between the inflammation and the oxidant stress in asthmatic airways is poor. Does oxidant stress contribute to the expression of asthmatic phenotypes independently of inflammation? If so, could asthmatics benefit from supplementation of antioxidants? These questions have been nagging us since our laboratory provided credible evidence of oxidant injury in the airways of allergic asthmatics ( ). The purpose of our study is to more precisely determine 1/ the pathophysiologic role of oxidative stress, and 2/ usefulness of antioxidant therapy using vitamin E in allergic asthma.
Interventions
- DRUG Natural source d-α-tocopheryl acetate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2006-12 |
| Est. Completion | 2011-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00581048
The ClinicalTrials.gov registry entry for NCT00581048 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Natural source d-α-tocopheryl acetate is the first listed.
NCT00581048 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00581048 about?
NCT00581048 is a clinical study titled "Study on the Role of Treatment With Vitamin E on Asthmatic Responses in Allergic Asthmatics". Asthma is a common respiratory disease of unknown etiology which currently affects approximately 7.5 % of the adult population ( ). Asthma is an inflammatory disorder of the airways. Airway inflammation is evident not only in patients with fatal asthma but also in mild asthmatics ( ). Oxidant stress...
What is the current status of trial NCT00581048?
This trial is currently completed. It is a NA study. The enrollment target is 33 participants. The study started on 2006-12. Estimated completion is 2011-10.
What interventions are being tested in trial NCT00581048?
The interventions under investigation include: Natural source d-α-tocopheryl acetate (DRUG).
Who is sponsoring clinical trial NCT00581048?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
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