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NCT00580970 · ClinicalTrials.gov registry record · Phase 2
Study of Effectiveness of Lovastatin to Prevent Radiation-Induced Rectal Injury
A Phase 2 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 2
- Development phase
- 73
- Enrollment target
NCT00580970: Completed Phase 2 study, sponsored by Virginia Commonwealth University.
NCT00580970 is a Phase 2 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 73 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (45% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00580970, a Phase 2 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 73 participants
- Enrollment target
Study Summary
Lovastatin may protect against late effects of radiation therapy in patients with prostate cancer
Primary Outcome
The primary endpoint of this study was percentage of participants with physician reported rectal toxicity ≥Grade 2 during the first 2 years after treatment. A one sided test will be conducted in order to evaluate reduction of risk from adding Lovastatin. The analysis is using a one-stage design, 5% level of significance, and 83% power.
Interventions
- DRUG lovastatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2007-04 |
| Est. Completion | 2015-08 |
| Phase | Phase 2 |
What the finished NCT00580970 record still lists
NCT00580970 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 73 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (45% lower).
The record links to 0 conditions, and to 1 intervention - of which lovastatin is the first listed.
NCT00580970 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00580970 about?
NCT00580970 is a clinical study titled "Study of Effectiveness of Lovastatin to Prevent Radiation-Induced Rectal Injury". Lovastatin may protect against late effects of radiation therapy in patients with prostate cancer
What is the current status of trial NCT00580970?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 73 participants. The study started on 2007-04. Estimated completion is 2015-08.
What interventions are being tested in trial NCT00580970?
The interventions under investigation include: lovastatin (DRUG).
Who is sponsoring clinical trial NCT00580970?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00580970's enrollment target sits among peer trials
73 924th of 2000 higher than 1,076 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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