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NCT00580957 · ClinicalTrials.gov registry record · NA
The Autonomic Nervous System and the Metabolic Syndrome
A NA study, sponsored by Vanderbilt University.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
NCT00580957 is a NA study that has completed, run by Vanderbilt University. The registered enrollment target is 56 participants.
The verdict
NCT00580957, a NA study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
Study Summary
The overall goal of this proposal is to determine the role of the autonomic nervous system in the insulin resistant state associated with obesity and the metabolic syndrome. Obesity results from an accumulation of excessive fat deposit due to increase caloric intake or decrease energy expenditure, this condition is usually associated with diseases such as hypertension or diabetes, a cluster known as the metabolic syndrome. The first step in the development of the metabolic syndrome is a resistance to the action of insulin. The mechanism underlying insulin resistance in obesity is still unknown, however some investigators have proposed that the autonomic nervous system, particularly the increase sympathetic activation in obesity may play an important role. We have extensive experience studying the role of the autonomic nervous system in the cardiovascular alterations associated with obesity by producing complete autonomic withdrawal with a drug named trimethaphan. We propose to use the same approach to study the role of the autonomic nervous system in the development of insulin resistance in obesity.
Interventions
- DRUG Blocked
- DRUG Intact
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2008-08 |
| Est. Completion | 2015-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00580957
The ClinicalTrials.gov registry entry for NCT00580957 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Blocked is the first listed.
NCT00580957 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00580957 about?
NCT00580957 is a clinical study titled "The Autonomic Nervous System and the Metabolic Syndrome". The overall goal of this proposal is to determine the role of the autonomic nervous system in the insulin resistant state associated with obesity and the metabolic syndrome. Obesity results from an accumulation of excessive fat deposit due to increase caloric intake or decrease energy expenditure, t...
What is the current status of trial NCT00580957?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2008-08. Estimated completion is 2015-05.
What interventions are being tested in trial NCT00580957?
The interventions under investigation include: Blocked (DRUG), Intact (DRUG).
Who is sponsoring clinical trial NCT00580957?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
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