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NCT00580905 · ClinicalTrials.gov registry record · Phase 1
Role of Adenosine in the Release of VEGF and Cytokines
A Phase 1 study, sponsored by Vanderbilt University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT00580905: Clinical Trial Phase 1 study, sponsored by Vanderbilt University.
NCT00580905 is a Phase 1 study that was terminated before completion, run by Vanderbilt University. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00580905, a Phase 1 study, was terminated before completion, sponsored by Vanderbilt University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to extend previous observations in animal models regarding the effects of adenosine in the release of cytokines to human subjects. We intend to accomplish this in two study protocols. In the first we will infuse intravenously adenosine and measure the plasma levels of inflammatory cytokines. In the second one, we will use a microdialysis technique to infuse intradermally small amounts of adenosine and will measure skin blood flow and will take a biopsy to measure levels of mRNA for cytokines.
Interventions
- DRUG Sodium Nitroprusside
- DRUG Adenosine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2007-06 |
| Est. Completion | 2017-01 |
| Phase | Phase 1 |
Why NCT00580905 stopped before completion
NCT00580905 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Sodium Nitroprusside is the first listed.
NCT00580905 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00580905 about?
NCT00580905 is a clinical study titled "Role of Adenosine in the Release of VEGF and Cytokines". The purpose of this study is to extend previous observations in animal models regarding the effects of adenosine in the release of cytokines to human subjects. We intend to accomplish this in two study protocols. In the first we will infuse intravenously adenosine and measure the plasma levels of in...
What is the current status of trial NCT00580905?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2007-06. Estimated completion is 2017-01.
What interventions are being tested in trial NCT00580905?
The interventions under investigation include: Sodium Nitroprusside (DRUG), Adenosine (DRUG).
Who is sponsoring clinical trial NCT00580905?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00580905's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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