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NCT00579969 · ClinicalTrials.gov registry record · Phase 2
Comparison of Latanoprost Vs. Timolol
A Phase 2 study, sponsored by University of Nebraska.
- Terminated
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
NCT00579969: Clinical Trial Phase 2 study, sponsored by University of Nebraska.
NCT00579969 is a Phase 2 study that was terminated before completion, run by University of Nebraska. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00579969, a Phase 2 study, was terminated before completion, sponsored by University of Nebraska.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
Study Summary
The primary purpose of this study is to show, through a controlled masked clinical study of subjects with ocular hypertension (OHT), that latanoprost increases the low uveoscleral drainage of aqueous humor back to normal levels, and timolol maleate reduces the formation of aqueous humor below normal. Both of these mechanisms will effectively reduce intraocular pressure (IOP). The secondary purpose is to assess the effects of both latanoprost and timolol maleate on the fluorophotometric outflow facility, and episcleral venous pressure and on all parameters over time.
Primary Outcome
Two drugs, Latanoprost and Timolol, will be compared in ocular hypertensive patients in their ability to lower ocular pressure at six months using a Goldmann applanation tonometer (GAT).
Interventions
- DRUG Latanoprost
- DRUG Timolol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2003-12 |
| Est. Completion | 2008-10 |
| Phase | Phase 2 |
Why NCT00579969 stopped before completion
NCT00579969 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 2 interventions - of which Latanoprost is the first listed.
NCT00579969 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00579969 about?
NCT00579969 is a clinical study titled "Comparison of Latanoprost Vs. Timolol". The primary purpose of this study is to show, through a controlled masked clinical study of subjects with ocular hypertension (OHT), that latanoprost increases the low uveoscleral drainage of aqueous humor back to normal levels, and timolol maleate reduces the formation of aqueous humor below normal...
What is the current status of trial NCT00579969?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2003-12. Estimated completion is 2008-10.
What interventions are being tested in trial NCT00579969?
The interventions under investigation include: Latanoprost (DRUG), Timolol (DRUG).
Who is sponsoring clinical trial NCT00579969?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00579969's enrollment target sits among peer trials
30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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