Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00575861 · ClinicalTrials.gov registry record · Phase 4
Zileuton and Exhaled Nitric Oxide in Asthmatics
A Phase 4 study, sponsored by Gelb, Arthur F., M.D..
- Completed
- Registry status
- Phase 4
- Development phase
- 19
- Enrollment target
NCT00575861: Completed Phase 4 study, sponsored by Gelb, Arthur F., M.D..
NCT00575861 is a Phase 4 study that has completed, run by Gelb, Arthur F., M.D.. The registered enrollment target is 19 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00575861, a Phase 4 study, has completed, sponsored by Gelb, Arthur F., M.D..
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 19 participants
- Enrollment target
Study Summary
Evaluate the additive role of zileuton 600mg qid to clinically stable asthmatics on Advair 250/50 bid. Since asthma is an endogenous inflammatory disease there usually is increased total exhaled, bronchial and alveolar nitric oxide which are markers of eosinophilic driven pathways of inflammation. The addition of zileuton which is a leukotriene synthesis inhibitor by itself or together with inhaled corticosteroids should reduce nitric oxide gas exchange.
Interventions
- DRUG zileuton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2005-09 |
| Est. Completion | 2007-11 |
| Phase | Phase 4 |
What the finished NCT00575861 record still lists
NCT00575861 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which zileuton is the first listed.
NCT00575861 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00575861 about?
NCT00575861 is a clinical study titled "Zileuton and Exhaled Nitric Oxide in Asthmatics". Evaluate the additive role of zileuton 600mg qid to clinically stable asthmatics on Advair 250/50 bid. Since asthma is an endogenous inflammatory disease there usually is increased total exhaled, bronchial and alveolar nitric oxide which are markers of eosinophilic driven pathways of inflammation. T...
What is the current status of trial NCT00575861?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 19 participants. The study started on 2005-09. Estimated completion is 2007-11.
What interventions are being tested in trial NCT00575861?
The interventions under investigation include: zileuton (DRUG).
Who is sponsoring clinical trial NCT00575861?
This trial is sponsored by Gelb, Arthur F., M.D., which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00575861's enrollment target sits among peer trials
19 1834th of 2000 higher than 159 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03207464 · 19 participants · Phase 1
Molecular Imaging of NET Using [C-11]MRB-PET in MS
- NCT04318717 · 19 participants · Phase 2
Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma
- NCT05103904 · 19 participants · Phase 2
Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant
- NCT05607407 · 19 participants · Phase 2
Methimazole in Patients With Progressive Glioblastoma
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia