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NCT00574535 · ClinicalTrials.gov registry record
Reproductive Hormones And Pre-Clinical Cardiovascular Disease (CVD) In Women
A clinical trial, sponsored by Cedars-Sinai Medical Center.
- Completed
- Registry status
- 269
- Enrollment target
NCT00574535 is a clinical trial that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 269 participants.
The verdict
NCT00574535 has completed, sponsored by Cedars-Sinai Medical Center.
- COMPLETED
- Registry status
- 269 participants
- Enrollment target
Study Summary
Heart disease is not just the number one killer of women, it is also a leading cause of disability. While it is generally believed that heart disease in women is a disease of old age, the stark reality is that heart disease is responsible for more deaths than breast cancer AT ALL AGES. Also, when young women develop heart disease, they are more likely to die or become disabled than their male peers. Identifying women at risk for heart disease is an important step toward reducing the impact of this disease. Although women can develop heart disease at any age, most women show signs and symptoms of disease about 10 years after men. For years, it has been thought that the reason for this lag is that women's hearts are protected by estrogen, and that when women go through menopause and lose their natural estrogen, they also lose their protection from heart disease. It has been assumed that if estrogen is replaced then protection will continue. These assumptions have not been proven. In fact, three large, randomized trials have shown no benefit from hormone replacement therapy in women known to have heart disease, and in fact have shown that hormone replacement may be harmful. To better understand the role of hormones and heart disease, the investigators propose to look at markers of heart disease in healthy women and compare this to their natural hormone levels. One of the markers known to be related to heart disease is carotid artery intima-medial thickness (c-IMT) which can be measured by creating an ultrasound picture of an artery in the neck. The investgators will use c-IMT scans and serum blood samples from women in the NIH-sponsored Los Angeles Atherosclerosis Study (LAAS), a large epidemiologic study that followed participants for 8 years. The proposed study will use risk factor information, serum samples and c-IMT scans collected from the female participants (about 269 women) over the 8 years of follow-up. The total sample size is 269 subjects, each of whom don
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 269 participants |
| Start Date | 1995-01 |
| Est. Completion | 2009-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00574535
The ClinicalTrials.gov registry entry for NCT00574535 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 269 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cedars-Sinai Medical Center, which has 339 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00574535 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00574535 about?
NCT00574535 is a clinical study titled "Reproductive Hormones And Pre-Clinical Cardiovascular Disease (CVD) In Women". Heart disease is not just the number one killer of women, it is also a leading cause of disability. While it is generally believed that heart disease in women is a disease of old age, the stark reality is that heart disease is responsible for more deaths than breast cancer AT ALL AGES. Also, when yo...
What is the current status of trial NCT00574535?
This trial is currently completed. The enrollment target is 269 participants. The study started on 1995-01. Estimated completion is 2009-12.
Who is sponsoring clinical trial NCT00574535?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
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