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NCT00574340 · ClinicalTrials.gov registry record · Early Phase 1

Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 4

A Early Phase 1 study, sponsored by University of Maryland, Baltimore.

Completed
Registry status
Early Phase 1
Development phase
20
Enrollment target

NCT00574340: Completed Early Phase 1 study, sponsored by University of Maryland, Baltimore.

NCT00574340 is a Early Phase 1 study that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 20 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00574340, a Early Phase 1 study, has completed, sponsored by University of Maryland, Baltimore.

COMPLETED
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target

Study Summary

Hypoglycemia (low blood glucose level) occurs frequently in intensively treated patients with diabetes. Although hypoglycemia was thought to occur almost exclusively in T1DM, with the advent of improved metabolic control in T2DM, the incidence of hypoglycemia is rising in these patients. Therefore in this application, we will test the novel hypothesis that prior hypoglycemia will result in (cardiovascular complications) during subsequent hypoglycemia.

Primary Outcome

A measure of the baseline arterial dilation on day 2 is compared to the post intervention measure of dilation of the brachial artery on Day 2.

Interventions

  • OTHER Hyperinsulinemic Hypoglycemic Clamp

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2007-05
Est. Completion 2011-04
Phase Early Phase 1
University of Maryland, Baltimore

560 total trials

What the finished NCT00574340 record still lists

NCT00574340 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 1 intervention - of which Hyperinsulinemic Hypoglycemic Clamp is the first listed.

NCT00574340 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00574340 about?

NCT00574340 is a clinical study titled "Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 4". Hypoglycemia (low blood glucose level) occurs frequently in intensively treated patients with diabetes. Although hypoglycemia was thought to occur almost exclusively in T1DM, with the advent of improved metabolic control in T2DM, the incidence of hypoglycemia is rising in these patients. Therefore i...

What is the current status of trial NCT00574340?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2007-05. Estimated completion is 2011-04.

What interventions are being tested in trial NCT00574340?

The interventions under investigation include: Hyperinsulinemic Hypoglycemic Clamp (OTHER).

Who is sponsoring clinical trial NCT00574340?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00574340's enrollment target sits among peer trials

20 1157th of 2000 higher than 709 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00574340, the US trial registry maintained by the National Library of Medicine. NCT00574340 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.