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NCT00574119 · ClinicalTrials.gov registry record · Phase 4
Effect of Aldosterone on Energy Starvation in Heart Failure
A Phase 4 study, sponsored by Vanderbilt University.
- Completed
- Registry status
- Phase 4
- Development phase
- 16
- Enrollment target
NCT00574119: Completed Phase 4 study, sponsored by Vanderbilt University.
NCT00574119 is a Phase 4 study that has completed, run by Vanderbilt University. The registered enrollment target is 16 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00574119, a Phase 4 study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 16 participants
- Enrollment target
Study Summary
We plan to study the concept of "energy starvation" in heart failure by evaluation of patients with nonischemic dilated cardiomyopathy (NIDCM) (heart failure with reduced heart pump function due to causes other than heart attack). We will use a combination of positron emission tomography and magnetic resonance imaging to study metabolism, anatomy, function, blood flow and efficiency, before and after 6 months' treatment with the drug spironolactone which blocks the deleterious effects of the hormone aldosterone on the myocardium (heart muscle).
Primary Outcome
WMI=\[left ventricular stroke work/decay rate of 11C-acetate\]
Interventions
- DRUG spironolactone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2007-12 |
| Est. Completion | 2012-07 |
| Phase | Phase 4 |
What the finished NCT00574119 record still lists
NCT00574119 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which spironolactone is the first listed.
NCT00574119 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00574119 about?
NCT00574119 is a clinical study titled "Effect of Aldosterone on Energy Starvation in Heart Failure". We plan to study the concept of "energy starvation" in heart failure by evaluation of patients with nonischemic dilated cardiomyopathy (NIDCM) (heart failure with reduced heart pump function due to causes other than heart attack). We will use a combination of positron emission tomography and magneti...
What is the current status of trial NCT00574119?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 16 participants. The study started on 2007-12. Estimated completion is 2012-07.
What interventions are being tested in trial NCT00574119?
The interventions under investigation include: spironolactone (DRUG).
Who is sponsoring clinical trial NCT00574119?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00574119's enrollment target sits among peer trials
16 1869th of 2000 higher than 121 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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