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NCT00573391 · ClinicalTrials.gov registry record · Phase 3

Study of Multiple Myeloma Patients Relapsing or Progressing After Autologous Transplantation on Total Therapy 2

A Phase 3 study, sponsored by University of Arkansas.

Terminated
Registry status
Phase 3
Development phase
5
Enrollment target

NCT00573391: Clinical Trial Phase 3 study, sponsored by University of Arkansas.

NCT00573391 is a Phase 3 study that was terminated before completion, run by University of Arkansas. The registered enrollment target is 5 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00573391, a Phase 3 study, was terminated before completion, sponsored by University of Arkansas.

TERMINATED
Registry status
Phase 3
Development phase
5 participants
Enrollment target

Study Summary

This study is being done to find out if the combination of VelcadeTM with melphalan and dexamethasone (VMD) will be as effective, or even more effective as it is in combination with thalidomide and dexamethasone (VTD).

Primary Outcome

due to low accrual rates, no analyses was done to compare the new combination of Velcade/Melphalan/Dexamethasone vs. Velcade/Thalidomide/Dexamethasone

Interventions

  • DRUG Velcade, Thalidomide, and Dexamethasone
  • DRUG Velcade, Melphalan, and Dexamethasone

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2006-08
Est. Completion 2008-07
Phase Phase 3
University of Arkansas

318 total trials

Why NCT00573391 stopped before completion

NCT00573391 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Velcade, Thalidomide, and Dexamethasone is the first listed.

NCT00573391 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00573391 about?

NCT00573391 is a clinical study titled "Study of Multiple Myeloma Patients Relapsing or Progressing After Autologous Transplantation on Total Therapy 2". This study is being done to find out if the combination of VelcadeTM with melphalan and dexamethasone (VMD) will be as effective, or even more effective as it is in combination with thalidomide and dexamethasone (VTD).

What is the current status of trial NCT00573391?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 5 participants. The study started on 2006-08. Estimated completion is 2008-07.

What interventions are being tested in trial NCT00573391?

The interventions under investigation include: Velcade, Thalidomide, and Dexamethasone (DRUG), Velcade, Melphalan, and Dexamethasone (DRUG).

Who is sponsoring clinical trial NCT00573391?

This trial is sponsored by University of Arkansas, which has 318 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00573391's enrollment target sits among peer trials

5 1997th of 2000 higher than 3 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00573391, the US trial registry maintained by the National Library of Medicine. NCT00573391 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.