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A Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT00570986 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine the safety and efficacy of 2 doses of ABT-874 versus placebo in the treatment of subjects with moderate to severe plaque psoriasis.
Conditions Studied
Interventions
- DRUG Placebo
- BIOLOGICAL ABT-874
Study Locations (20)
California
- Site Reference ID/Investigator# 6591 — Bakersfield
- Site Reference ID/Investigator# 6710 — Fresno
- Site Reference ID/Investigator# 7885 — Irvine
- Site Reference ID/Investigator# 6872 — Los Angeles
- Site Reference ID/Investigator# 7669 — Oceanside
- Site Reference ID/Investigator# 6821 — San Diego
- Site Reference ID/Investigator# 6832 — San Diego
- Site Reference ID/Investigator# 7305 — San Diego
- Site Reference ID/Investigator# 7990 — San Francisco
- Site Reference ID/Investigator# 6711 — Santa Monica
- Site Reference ID/Investigator# 8139 — Torrance
- Site Reference ID/Investigator# 7167 — Vallejo
Alabama
- Site Reference ID/Investigator# 6579 — Birmingham
- Site Reference ID/Investigator# 6697 — Birmingham
- Site Reference ID/Investigator# 7015 — Huntsville
Arizona
- Site Reference ID/Investigator# 6728 — Scottsdale
- Site Reference ID/Investigator# 6584 — Tucson
Colorado
- Site Reference ID/Investigator# 7302 — Denver
- Site Reference ID/Investigator# 6921 — Longmont
Arkansas
- Site Reference ID/Investigator# 6696 — Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,465 participants |
| Start Date | 2007-11 |
| Est. Completion | 2009-06 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00570986
The ClinicalTrials.gov registry entry for NCT00570986 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,465 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie (prior sponsor, Abbott), which has 16 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00570986 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00570986 about?
NCT00570986 is a clinical study titled "A Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis". The purpose of this study is to determine the safety and efficacy of 2 doses of ABT-874 versus placebo in the treatment of subjects with moderate to severe plaque psoriasis.
What is the current status of trial NCT00570986?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,465 participants. The study started on 2007-11. Estimated completion is 2009-06.
What conditions does trial NCT00570986 study?
This clinical trial studies the following conditions: Plaque Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00570986?
The interventions under investigation include: Placebo (DRUG), ABT-874 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00570986?
This trial is sponsored by AbbVie (prior sponsor, Abbott), which has 16 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00570986 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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