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NCT00555464 · ClinicalTrials.gov registry record · Phase 2
Clinical Trial of Vincristine vs. Prednisolone for Treatment of Complicated Hemangiomas
A Phase 2 study, sponsored by Medical College of Wisconsin.
- Terminated
- Registry status
- Phase 2
- Development phase
- 8
- Enrollment target
NCT00555464: Clinical Trial Phase 2 study, sponsored by Medical College of Wisconsin.
NCT00555464 is a Phase 2 study that was terminated before completion, run by Medical College of Wisconsin. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00555464, a Phase 2 study, was terminated before completion, sponsored by Medical College of Wisconsin.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 8 participants
- Enrollment target
Study Summary
The goal of this study is to determine the safety and efficacy of Prednisolone and Vincristine for treatment of large, complicated infantile hemangiomas. The diagnostic, therapeutic and response criteria experimentally determined in this study will be used as a framework for future infantile hemangioma studies.
Primary Outcome
Response of IH not confined to the dermis will be coded using the following criteria: Progressive disease: \>40% increase in volume by MRI, Partial response: \>65% reduction in volume by MRI, Complete response: no visual or radiographic evidence of disease, Stable disease: none of the above or \<40% increase or \<65% decrease in volume by MRI. Response of superficial IH will be coded using the following criteria (based on RECIST): Progressive disease: \>30% increase in IH size, Partial response
Interventions
- DRUG Vincristine
- DRUG Prednisone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2007-11 |
| Est. Completion | 2012-12 |
| Phase | Phase 2 |
Why NCT00555464 stopped before completion
NCT00555464 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Vincristine is the first listed.
NCT00555464 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00555464 about?
NCT00555464 is a clinical study titled "Clinical Trial of Vincristine vs. Prednisolone for Treatment of Complicated Hemangiomas". The goal of this study is to determine the safety and efficacy of Prednisolone and Vincristine for treatment of large, complicated infantile hemangiomas. The diagnostic, therapeutic and response criteria experimentally determined in this study will be used as a framework for future infantile hemangi...
What is the current status of trial NCT00555464?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2007-11. Estimated completion is 2012-12.
What interventions are being tested in trial NCT00555464?
The interventions under investigation include: Vincristine (DRUG), Prednisone (DRUG).
Who is sponsoring clinical trial NCT00555464?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00555464's enrollment target sits among peer trials
8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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