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NCT00554203 · ClinicalTrials.gov registry record · NA
Sulfasalazine and Endothelial Function
A NA study, sponsored by Boston University.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT00554203: Completed NA study, sponsored by Boston University.
NCT00554203 is a NA study that has completed, run by Boston University. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00554203, a NA study, has completed, sponsored by Boston University.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Experimental studies suggest that systemic inflammation leads to endothelial dysfunction and atherosclerosis. This study will examine the effects of the anti-inflammatory drug sulfasalazine on endothelial function in patients with coronary artery disease. Subjects will be treated with sulfasalazine or to placebo for six weeks. After a two-week rest period, subjects will cross over to the alternative treatment. Endothelium-dependent flow-mediated dilation of the brachial artery will be studied before and after each drug. We hypothesize that anti-inflammatory therapy will reverse endothelial dysfunction in patients with coronary artery disease.
Interventions
- DRUG Sulfasalazine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2003-07 |
| Est. Completion | 2007-12 |
| Phase | NA |
What the finished NCT00554203 record still lists
NCT00554203 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Sulfasalazine is the first listed.
NCT00554203 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00554203 about?
NCT00554203 is a clinical study titled "Sulfasalazine and Endothelial Function". Experimental studies suggest that systemic inflammation leads to endothelial dysfunction and atherosclerosis. This study will examine the effects of the anti-inflammatory drug sulfasalazine on endothelial function in patients with coronary artery disease. Subjects will be treated with sulfasalazine ...
What is the current status of trial NCT00554203?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2003-07. Estimated completion is 2007-12.
What interventions are being tested in trial NCT00554203?
The interventions under investigation include: Sulfasalazine (DRUG).
Who is sponsoring clinical trial NCT00554203?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00554203's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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