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NCT00554203 · ClinicalTrials.gov registry record · NA

Sulfasalazine and Endothelial Function

A NA study, sponsored by Boston University.

Completed
Registry status
NA
Development phase
60
Enrollment target

NCT00554203 is a NA study that has completed, run by Boston University. The registered enrollment target is 60 participants.

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The verdict

NCT00554203, a NA study, has completed, sponsored by Boston University.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target

Study Summary

Experimental studies suggest that systemic inflammation leads to endothelial dysfunction and atherosclerosis. This study will examine the effects of the anti-inflammatory drug sulfasalazine on endothelial function in patients with coronary artery disease. Subjects will be treated with sulfasalazine or to placebo for six weeks. After a two-week rest period, subjects will cross over to the alternative treatment. Endothelium-dependent flow-mediated dilation of the brachial artery will be studied before and after each drug. We hypothesize that anti-inflammatory therapy will reverse endothelial dysfunction in patients with coronary artery disease.

Interventions

  • DRUG Sulfasalazine

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2003-07
Est. Completion 2007-12
Phase NA

Sponsor

Boston University

185 total trials

What the Registry Record Tells You About NCT00554203

The ClinicalTrials.gov registry entry for NCT00554203 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Sulfasalazine is the first listed.

NCT00554203 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00554203 about?

NCT00554203 is a clinical study titled "Sulfasalazine and Endothelial Function". Experimental studies suggest that systemic inflammation leads to endothelial dysfunction and atherosclerosis. This study will examine the effects of the anti-inflammatory drug sulfasalazine on endothelial function in patients with coronary artery disease. Subjects will be treated with sulfasalazine ...

What is the current status of trial NCT00554203?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2003-07. Estimated completion is 2007-12.

What interventions are being tested in trial NCT00554203?

The interventions under investigation include: Sulfasalazine (DRUG).

Who is sponsoring clinical trial NCT00554203?

This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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