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NCT00553995 · ClinicalTrials.gov registry record · Phase 1
Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction
A Phase 1 study, sponsored by Boston University.
- Completed
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
NCT00553995: Completed Phase 1 study, sponsored by Boston University.
NCT00553995 is a Phase 1 study that has completed, run by Boston University. The registered enrollment target is 60 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00553995, a Phase 1 study, has completed, sponsored by Boston University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
Study Summary
Physical inactivity induces vascular dysfunction and glucose intolerance during five days of bed rest. This study will investigate the effects of salsalate on these responses. Subjects will be randomized to treatment with salsalate or placebo for four days prior to initiation of bed rest. Vascular function in the brachial artery will be determined by ultrasound prior to treatment and before and after the 5-day bed rest protocol. We hypothesize that treatment with salsalate will be associated with protection again the development of glucose intolerance and vascular dysfunction in this setting.
Interventions
- DRUG Placebo
- DRUG salsalate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2008-05 |
| Est. Completion | 2014-12-01 |
| Phase | Phase 1 |
What the finished NCT00553995 record still lists
NCT00553995 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00553995 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00553995 about?
NCT00553995 is a clinical study titled "Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction". Physical inactivity induces vascular dysfunction and glucose intolerance during five days of bed rest. This study will investigate the effects of salsalate on these responses. Subjects will be randomized to treatment with salsalate or placebo for four days prior to initiation of bed rest. Vascular f...
What is the current status of trial NCT00553995?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2008-05. Estimated completion is 2014-12-01.
What interventions are being tested in trial NCT00553995?
The interventions under investigation include: Placebo (DRUG), salsalate (DRUG).
Who is sponsoring clinical trial NCT00553995?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00553995's enrollment target sits among peer trials
60 831st of 2000 higher than 1,106 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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