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NCT00553462 · ClinicalTrials.gov registry record · Phase 2

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

A Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 2
Development phase
78
Enrollment target

NCT00553462 is a Phase 2 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 78 participants.

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The verdict

NCT00553462, a Phase 2 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 2
Development phase
78 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Erlotinib may make tumor cells more sensitive to radiation therapy. Giving carboplatin and paclitaxel albumin-stabilized nanoparticle formulation together with radiation therapy and erlotinib may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving carboplatin and paclitaxel albumin-stabilized nanoparticle formulation together with radiation therapy and erlotinib works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery.

Interventions

  • DRUG carboplatin
  • RADIATION radiation therapy
  • DRUG paclitaxel albumin-stabilized nanoparticle formulation
  • DRUG erlotinib hydrochloride

Trial Details

FieldValue
Enrollment Target 78 participants
Start Date 2008-03
Est. Completion 2017-06-15
Phase Phase 2

What the Registry Record Tells You About NCT00553462

The ClinicalTrials.gov registry entry for NCT00553462 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 78 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance for Clinical Trials in Oncology, which has 446 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which carboplatin is the first listed.

NCT00553462 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00553462 about?

NCT00553462 is a clinical study titled "Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery". RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cell...

What is the current status of trial NCT00553462?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 78 participants. The study started on 2008-03. Estimated completion is 2017-06-15.

What interventions are being tested in trial NCT00553462?

The interventions under investigation include: carboplatin (DRUG), radiation therapy (RADIATION), paclitaxel albumin-stabilized nanoparticle formulation (DRUG), erlotinib hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00553462?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.