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NCT00552071 · ClinicalTrials.gov registry record · Phase 4

Ultrasound Guided Octreotide LAR Injection in Acromegaly

A Phase 4 study, sponsored by Cedars-Sinai Medical Center.

Completed
Registry status
Phase 4
Development phase
15
Enrollment target

NCT00552071: Completed Phase 4 study, sponsored by Cedars-Sinai Medical Center.

NCT00552071 is a Phase 4 study that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 15 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00552071, a Phase 4 study, has completed, sponsored by Cedars-Sinai Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
15 participants
Enrollment target

Study Summary

Approximately half of patients with acromegaly do not respond to treatment with somatostatin receptor ligands such as octreotide LAR. This may be due to inadequate drug delivery if the standard of care regular injection is inaccurately delivered in the intramuscular (IM) compartment. Ultrasound guidance of IM injections may improve accuracy of placement of IM injections and increase drug levels, thereby improving efficacy of octreotide LAR for the treatment of acromegaly. The purpose of this study is to determine whether octreotide LAR drug levels differ if given by ultrasound-guided IM injection or by regular IM injection in patients with acromegaly.

Primary Outcome

Venous sampling was performed at each visit immediately prior to each IM injection. Levels were measured at each visit and mean for the group was calculated after each treatment phase.

Interventions

  • DRUG Octreotide LAR 30 MG Injection

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2007-07
Est. Completion 2014-03
Phase Phase 4
Cedars-Sinai Medical Center

339 total trials

What the finished NCT00552071 record still lists

NCT00552071 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Octreotide LAR 30 MG Injection is the first listed.

NCT00552071 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00552071 about?

NCT00552071 is a clinical study titled "Ultrasound Guided Octreotide LAR Injection in Acromegaly". Approximately half of patients with acromegaly do not respond to treatment with somatostatin receptor ligands such as octreotide LAR. This may be due to inadequate drug delivery if the standard of care regular injection is inaccurately delivered in the intramuscular (IM) compartment. Ultrasound guid...

What is the current status of trial NCT00552071?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 15 participants. The study started on 2007-07. Estimated completion is 2014-03.

What interventions are being tested in trial NCT00552071?

The interventions under investigation include: Octreotide LAR 30 MG Injection (DRUG).

Who is sponsoring clinical trial NCT00552071?

This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00552071's enrollment target sits among peer trials

15 1880th of 2000 higher than 100 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00552071, the US trial registry maintained by the National Library of Medicine. NCT00552071 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.