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NCT00538083 · ClinicalTrials.gov registry record · Phase 1
Cocoa and Endothelial Function in Adults With Elevated BMI
A Phase 1 study of Cardioprotection, sponsored by Griffin Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT00538083 is a Phase 1 study of Cardioprotection that has completed, run by Griffin Hospital. The registered enrollment target is 45 participants. The trial reports 1 study location across 1 state.
The verdict
NCT00538083, a Phase 1 study of Cardioprotection, has completed, sponsored by Griffin Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
Cardiovascular disease is the leading cause of death in the United States. Studies have shown that obesity is an important risk factor for development of cardiovascular disease. Endothelial dysfunction, a pathologic feature of obesity, predicts the occurrence of cardiovascular disease. Recent research findings indicate that consumption of cocoa exerts cardioprotective effects, which include increasing HDL levels, reduction in systolic BP, inhibition of platelet aggregation/activity and activation of endothelial nitric oxide synthase. Proposed is a randomized controlled trial consisting of 4 phases designed to examine the dose-response, and the acute and sustained effects of cocoa consumption on endothelial function as a marker of cardiovascular disease risk in 45 otherwise healthy adults with a BMI 25-35kg/m2.
Conditions Studied
Interventions
- OTHER Chocolate
Study Locations (1)
Connecticut
- Griffin Hospital - Derby
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2005-08 |
| Est. Completion | 2006-05 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00538083
The ClinicalTrials.gov registry entry for NCT00538083 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Griffin Hospital, which has 22 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cardioprotection appearing as the primary indexed condition, and to 1 intervention - of which Chocolate is the first listed.
NCT00538083 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT00538083 about?
NCT00538083 is a clinical study titled "Cocoa and Endothelial Function in Adults With Elevated BMI". Cardiovascular disease is the leading cause of death in the United States. Studies have shown that obesity is an important risk factor for development of cardiovascular disease. Endothelial dysfunction, a pathologic feature of obesity, predicts the occurrence of cardiovascular disease. Recent resear...
What is the current status of trial NCT00538083?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2005-08. Estimated completion is 2006-05.
What conditions does trial NCT00538083 study?
This clinical trial studies the following conditions: Cardioprotection.
What interventions are being tested in trial NCT00538083?
The interventions under investigation include: Chocolate (OTHER).
Who is sponsoring clinical trial NCT00538083?
This trial is sponsored by Griffin Hospital, which has 22 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00538083 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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