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NCT00537043 · ClinicalTrials.gov registry record · Phase 1
A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure
A Phase 1 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT00537043: Completed Phase 1 study, sponsored by GlaxoSmithKline.
NCT00537043 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00537043, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
Carvedilol controlled release is a marketed drug to treat high blood pressure. This study is to compare carvedilol controlled release to carvedilol controlled release plus lisinopril (fixed-dose combination) after repeat dosing in patients with high blood pressure. This is to make sure that when carvedilol controlled release is given with lisinopril it acts the same in the body as when given alone. The study will also assess the safety and tolerability of the fixed-dose combination.
Interventions
- DRUG SK&F-105517 (COREG CR FDC)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2007-10 |
| Est. Completion | 2008-01 |
| Phase | Phase 1 |
What the finished NCT00537043 record still lists
NCT00537043 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 1 intervention - of which SK&F-105517 (COREG CR FDC) is the first listed.
NCT00537043 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00537043 about?
NCT00537043 is a clinical study titled "A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure". Carvedilol controlled release is a marketed drug to treat high blood pressure. This study is to compare carvedilol controlled release to carvedilol controlled release plus lisinopril (fixed-dose combination) after repeat dosing in patients with high blood pressure. This is to make sure that when car...
What is the current status of trial NCT00537043?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2007-10. Estimated completion is 2008-01.
What interventions are being tested in trial NCT00537043?
The interventions under investigation include: SK&F-105517 (COREG CR FDC) (DRUG).
Who is sponsoring clinical trial NCT00537043?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00537043's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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