Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00535587 · ClinicalTrials.gov registry record · Phase 2

Testing Mestinon and Exercise in Fibromyalgia

A Phase 2 study, sponsored by Oregon Health and Science University.

Completed
Registry status
Phase 2
Development phase
178
Enrollment target

NCT00535587: Completed Phase 2 study, sponsored by Oregon Health and Science University.

NCT00535587 is a Phase 2 study that has completed, run by Oregon Health and Science University. The registered enrollment target is 178 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (34% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00535587, a Phase 2 study, has completed, sponsored by Oregon Health and Science University.

COMPLETED
Registry status
Phase 2
Development phase
178 participants
Enrollment target

Study Summary

The purpose of this trial was to test the combined and independent effects of 6 months of exercise and Mestinon in people with fibromyalgia. Specifically, we wanted to determine if Mestinon helped people with fibromyalgia have an easier time exercising and if their symptoms improved by the end of the trial.

Primary Outcome

Serum growth hormone at peak V02/treadmill

Interventions

  • BEHAVIORAL Attention Control
  • BEHAVIORAL Exercise
  • DRUG pyridostigmine
  • DRUG Placibo

Trial Details

FieldValue
Enrollment Target 178 participants
Start Date 2002-09
Est. Completion 2008-06
Phase Phase 2

What the finished NCT00535587 record still lists

NCT00535587 is an interventional study that assigns participants to a tested intervention. The registered 178 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (34% higher).

The record links to 0 conditions, and to 4 interventions - of which Attention Control is the first listed.

NCT00535587 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00535587 about?

NCT00535587 is a clinical study titled "Testing Mestinon and Exercise in Fibromyalgia". The purpose of this trial was to test the combined and independent effects of 6 months of exercise and Mestinon in people with fibromyalgia. Specifically, we wanted to determine if Mestinon helped people with fibromyalgia have an easier time exercising and if their symptoms improved by the end of th...

What is the current status of trial NCT00535587?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 178 participants. The study started on 2002-09. Estimated completion is 2008-06.

What interventions are being tested in trial NCT00535587?

The interventions under investigation include: Attention Control (BEHAVIORAL), Exercise (BEHAVIORAL), pyridostigmine (DRUG), Placibo (DRUG).

Who is sponsoring clinical trial NCT00535587?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00535587's enrollment target sits among peer trials

178 391st of 2000 higher than 1,607 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03642002 · 178 participants · NA

    The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU

  • NCT04227847 · 178 participants · Phase 1

    A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

  • NCT04855214 · 178 participants

    Evaluating the Experience of Upper Limb Prosthesis Use

  • NCT05391126 · 178 participants · NA

    GENOCARE: A Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00535587, the US trial registry maintained by the National Library of Medicine. NCT00535587 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.