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NCT00528645 · ClinicalTrials.gov registry record · Phase 2

AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
23
Enrollment target

NCT00528645: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00528645 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 23 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00528645, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
23 participants
Enrollment target

Study Summary

AZD0530 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. This phase II study is studying how well giving AZD0530 works in treating patients with extensive-stage small cell lung cancer.

Primary Outcome

The progression-free survival (PFS) rate at 12 weeks will be estimated by calculating the number of patients that are alive and progression-free at 12 weeks post-registration divided by the total number of evaluable patients and multiplied by 100. All patients meeting the eligibility criteria who have signed a consent form, begun AZD0530 treatment, and are not lost to follow-up before 12 weeks, will be considered evaluable for the 12-week progression-free survival (PFS) rate. Progression is def

Interventions

  • DRUG saracatinib

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2007-11
Est. Completion 2013-05
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00528645 record still lists

NCT00528645 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which saracatinib is the first listed.

NCT00528645 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00528645 about?

NCT00528645 is a clinical study titled "AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer". AZD0530 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. This phase II study is studying how well giving AZD0530 works in treating patients with extensive-stage small cell lung cancer.

What is the current status of trial NCT00528645?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2007-11. Estimated completion is 2013-05.

What interventions are being tested in trial NCT00528645?

The interventions under investigation include: saracatinib (DRUG).

Who is sponsoring clinical trial NCT00528645?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00528645's enrollment target sits among peer trials

23 1784th of 2000 higher than 211 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00528645, the US trial registry maintained by the National Library of Medicine. NCT00528645 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.