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NCT00522301 · ClinicalTrials.gov registry record · Phase 2

Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission

A Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT00522301: Clinical Trial Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

NCT00522301 is a Phase 2 study that was terminated before completion, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00522301, a Phase 2 study, was terminated before completion, sponsored by Memorial Sloan Kettering Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well sorafenib works in treating patients with ovarian epithelial cancer, fallopian tube cancer, or peritoneal cancer in at least the second remission.

Primary Outcome

All 5 patients experienced a rash. As a result, all 5 were either advised to withdraw from the protocol, or withdrew themselves from the protocol. The outcome was not met.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER immunohistochemistry staining method
  • OTHER pharmacological study
  • OTHER immunoenzyme technique
  • DRUG sorafenib tosylate

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2007-07
Est. Completion 2008-03
Phase Phase 2
Memorial Sloan Kettering Cancer Center

1,884 total trials

Why NCT00522301 stopped before completion

NCT00522301 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT00522301 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00522301 about?

NCT00522301 is a clinical study titled "Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission". RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well sorafenib works in treating patients with ovarian epithelial cancer, fallopian tube cancer, or pe...

What is the current status of trial NCT00522301?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2007-07. Estimated completion is 2008-03.

What interventions are being tested in trial NCT00522301?

The interventions under investigation include: laboratory biomarker analysis (OTHER), immunohistochemistry staining method (OTHER), pharmacological study (OTHER), immunoenzyme technique (OTHER), sorafenib tosylate (DRUG).

Who is sponsoring clinical trial NCT00522301?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00522301's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00522301, the US trial registry maintained by the National Library of Medicine. NCT00522301 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.