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NCT00518882 · ClinicalTrials.gov registry record · Phase 3

Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes

A Phase 3 study, sponsored by Novo Nordisk A/S.

Completed
Registry status
Phase 3
Development phase
467
Enrollment target

NCT00518882: Completed Phase 3 study, sponsored by Novo Nordisk A/S.

NCT00518882 is a Phase 3 study that has completed, run by Novo Nordisk A/S. The registered enrollment target is 467 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00518882, a Phase 3 study, has completed, sponsored by Novo Nordisk A/S.

COMPLETED
Registry status
Phase 3
Development phase
467 participants
Enrollment target

Study Summary

This trial is conducted in Europe and the United States of America (USA). The aim of this trial is to compare the effect on glycaemic control of liraglutide or exenatide when added to subject's ongoing OAD (oral anti-diabetic drug) treatment of either metformin, sulphonylurea or a combination of both in subjects with type 2 diabetes. Two trial periods: A 26 week randomised, followed by a 52 week extension (14 + 38 weeks) where all subjects received liraglutide + OAD after previous randomisation to either liraglutide or exenatide, both combined with OAD treatment.

Primary Outcome

Percentage point change in glycosylated A1c (HbA1c) from baseline (week 0) to 26 weeks (end of randomisation)

Interventions

  • DRUG liraglutide
  • DRUG exenatide

Trial Details

FieldValue
Enrollment Target 467 participants
Start Date 2007-08
Est. Completion 2009-04
Phase Phase 3
Novo Nordisk A/S

431 total trials

What the finished NCT00518882 record still lists

NCT00518882 is an interventional study that assigns participants to a tested intervention. The registered 467 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 2 interventions - of which liraglutide is the first listed.

NCT00518882 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00518882 about?

NCT00518882 is a clinical study titled "Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes". This trial is conducted in Europe and the United States of America (USA). The aim of this trial is to compare the effect on glycaemic control of liraglutide or exenatide when added to subject's ongoing OAD (oral anti-diabetic drug) treatment of either metformin, sulphonylurea or a combination of bot...

What is the current status of trial NCT00518882?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 467 participants. The study started on 2007-08. Estimated completion is 2009-04.

What interventions are being tested in trial NCT00518882?

The interventions under investigation include: liraglutide (DRUG), exenatide (DRUG).

Who is sponsoring clinical trial NCT00518882?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00518882's enrollment target sits among peer trials

467 816th of 2000 higher than 1,185 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00518882, the US trial registry maintained by the National Library of Medicine. NCT00518882 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.