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NCT00518466 · ClinicalTrials.gov registry record · Phase 1
Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults
A Phase 1 study, sponsored by VIVUS.
- Completed
- Registry status
- Phase 1
- Development phase
- 64
- Enrollment target
NCT00518466: Completed Phase 1 study, sponsored by VIVUS.
NCT00518466 is a Phase 1 study that has completed, run by VIVUS. The registered enrollment target is 64 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00518466, a Phase 1 study, has completed, sponsored by VIVUS.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 64 participants
- Enrollment target
Study Summary
The primary objective of this study is to describe the single- and multiple-dose pharmacokinetic profiles of two novel formulations of topiramate and commercially available immediate release topiramate, all dosed with immediate release phentermine.
Interventions
- DRUG topiramate
- DRUG phentermine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2007-07 |
| Est. Completion | 2007-12 |
| Phase | Phase 1 |
What the finished NCT00518466 record still lists
NCT00518466 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which topiramate is the first listed.
NCT00518466 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00518466 about?
NCT00518466 is a clinical study titled "Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults". The primary objective of this study is to describe the single- and multiple-dose pharmacokinetic profiles of two novel formulations of topiramate and commercially available immediate release topiramate, all dosed with immediate release phentermine.
What is the current status of trial NCT00518466?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 64 participants. The study started on 2007-07. Estimated completion is 2007-12.
What interventions are being tested in trial NCT00518466?
The interventions under investigation include: topiramate (DRUG), phentermine (DRUG).
Who is sponsoring clinical trial NCT00518466?
This trial is sponsored by VIVUS, which has 35 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00518466's enrollment target sits among peer trials
64 808th of 2000 higher than 1,181 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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