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NCT00517192 · ClinicalTrials.gov registry record · Phase 3

Comparison of TPV/r to DRV/r in Triple Class Experienced Patient With Resistance to > 1 PI

A Phase 3 study, sponsored by Boehringer Ingelheim.

Terminated
Registry status
Phase 3
Development phase
40
Enrollment target

NCT00517192: Clinical Trial Phase 3 study, sponsored by Boehringer Ingelheim.

NCT00517192 is a Phase 3 study that was terminated before completion, run by Boehringer Ingelheim. The registered enrollment target is 40 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00517192, a Phase 3 study, was terminated before completion, sponsored by Boehringer Ingelheim.

TERMINATED
Registry status
Phase 3
Development phase
40 participants
Enrollment target

Study Summary

The objective of this study is to compare the efficacy and safety of Tipranavir/ritonavir (TPV/r, 500mg/200mg twice daily) to the safety and efficacy of Darunavir/ritonavir (DRV/r 600 mg /100 mg twice daily) in combination with investigator selected optimised background regimens in patients who are three-class (Nucleoside reverse transcriptase inhibitors (NRTI), Nonnucleoside reverse transcriptase inhibitors (NNRTI), and Protease inhibitor (PI)) treatment-experienced (a minimum of 3-months duration for each class) with resistance to more than one PI on the screening virtual phenotype resistance testing.

Interventions

  • DRUG Ritonavir
  • DRUG Darunavir
  • DRUG Tipranavir

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2007-09
Phase Phase 3
Boehringer Ingelheim

515 total trials

Why NCT00517192 stopped before completion

NCT00517192 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 3 interventions - of which Ritonavir is the first listed.

NCT00517192 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00517192 about?

NCT00517192 is a clinical study titled "Comparison of TPV/r to DRV/r in Triple Class Experienced Patient With Resistance to > 1 PI". The objective of this study is to compare the efficacy and safety of Tipranavir/ritonavir (TPV/r, 500mg/200mg twice daily) to the safety and efficacy of Darunavir/ritonavir (DRV/r 600 mg /100 mg twice daily) in combination with investigator selected optimised background regimens in patients who are ...

What is the current status of trial NCT00517192?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 40 participants. The study started on 2007-09.

What interventions are being tested in trial NCT00517192?

The interventions under investigation include: Ritonavir (DRUG), Darunavir (DRUG), Tipranavir (DRUG).

Who is sponsoring clinical trial NCT00517192?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00517192's enrollment target sits among peer trials

40 1878th of 2000 higher than 103 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00517192, the US trial registry maintained by the National Library of Medicine. NCT00517192 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.