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NCT00515710 · ClinicalTrials.gov registry record

LTFU for Gene Transfer Subjects With Hemophilia B

A clinical trial, sponsored by Spark Therapeutics.

Completed
Registry status
4
Enrollment target

NCT00515710 is a clinical trial that has completed, run by Spark Therapeutics. The registered enrollment target is 4 participants.

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The verdict

NCT00515710 has completed, sponsored by Spark Therapeutics.

COMPLETED
Registry status
4 participants
Enrollment target

Study Summary

Several subjects enrolled in a multi-site, gene transfer clinical study to evaluate the intrahepatic administration of AAV2-hFIX16 vector for the treatment of severe hemophilia B between 2001 and 2009. As the US FDA has established guidelines for the long-term follow-up (LTFU) of subjects receiving investigational gene therapy products, this protocol seeks to characterize the clinical outcome and the type and seriousness of adverse events following the AAV gene transfer. The primary study tools will consist of annual history/physical examination and blood tests, as well as periodic liver ultrasound, to characterize clinical outcomes. Where possible, data will be obtained for up to 15 years following hepatic AAV2-hFIX16 gene transfer.

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2007-08
Est. Completion 2017-12

Sponsor

Spark Therapeutics

13 total trials

What the Registry Record Tells You About NCT00515710

The ClinicalTrials.gov registry entry for NCT00515710 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Spark Therapeutics, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00515710 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00515710 about?

NCT00515710 is a clinical study titled "LTFU for Gene Transfer Subjects With Hemophilia B". Several subjects enrolled in a multi-site, gene transfer clinical study to evaluate the intrahepatic administration of AAV2-hFIX16 vector for the treatment of severe hemophilia B between 2001 and 2009. As the US FDA has established guidelines for the long-term follow-up (LTFU) of subjects receiving ...

What is the current status of trial NCT00515710?

This trial is currently completed. The enrollment target is 4 participants. The study started on 2007-08. Estimated completion is 2017-12.

Who is sponsoring clinical trial NCT00515710?

This trial is sponsored by Spark Therapeutics, which has 13 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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