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NCT00504894 · ClinicalTrials.gov registry record · Phase 4

Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes

A Phase 4 study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
Phase 4
Development phase
60
Enrollment target

NCT00504894 is a Phase 4 study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 60 participants.

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The verdict

NCT00504894, a Phase 4 study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
Phase 4
Development phase
60 participants
Enrollment target

Study Summary

This study involves 60 healthy volunteers aged between 18 and 50 recruited from the general community. It involves doing a set of simple memory tests while inside a fMRI machine. The subject is given a very low dose of an anesthetic drug intravenously while in the scanner. The subject then sees a sequence of pictures on a screen, and presses a button if they remember seeing the picture before. While this is happening, the scanner will be capturing images that tell us what parts of the brain are active. Hypothesis: patterns of hippocampal and amygdala activation during the encoding and retrieval of memory,as measured by fMRI, will be altered by intravenous anesthetics such that suppression of hippocampal and amygdala activities will be dissociable. This dissociation pattern will be different between the drugs propofol and thiopental.

Interventions

  • DRUG Placebo
  • DRUG Propofol
  • DRUG Thiopental

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2007-03
Est. Completion 2013-11
Phase Phase 4

What the Registry Record Tells You About NCT00504894

The ClinicalTrials.gov registry entry for NCT00504894 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00504894 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00504894 about?

NCT00504894 is a clinical study titled "Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes". This study involves 60 healthy volunteers aged between 18 and 50 recruited from the general community. It involves doing a set of simple memory tests while inside a fMRI machine. The subject is given a very low dose of an anesthetic drug intravenously while in the scanner. The subject then sees a se...

What is the current status of trial NCT00504894?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2007-03. Estimated completion is 2013-11.

What interventions are being tested in trial NCT00504894?

The interventions under investigation include: Placebo (DRUG), Propofol (DRUG), Thiopental (DRUG).

Who is sponsoring clinical trial NCT00504894?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.