Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00503581 · ClinicalTrials.gov registry record · Phase 2
Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia
A Phase 2 study, sponsored by Gynecologic Oncology Group.
- Terminated
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
NCT00503581: Clinical Trial Phase 2 study, sponsored by Gynecologic Oncology Group.
NCT00503581 is a Phase 2 study that was terminated before completion, run by Gynecologic Oncology Group. The registered enrollment target is 9 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00503581, a Phase 2 study, was terminated before completion, sponsored by Gynecologic Oncology Group.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
Study Summary
This randomized phase II trial is studying how well megestrol works in treating patients with endometrial neoplasia or endometrial hyperplasia. Estrogen can cause the growth of endometrial cancer cells. Hormone therapy using megestrol may fight endometrial cancer by blocking the use of estrogen by the abnormal cells.
Primary Outcome
Treated and eligible participants. This study had 0 participants that completed treatment, therefore no analysis was done. Study closed prior to completion. Central blinded review was not performed for any participants in the study.
Interventions
- OTHER Quality-of-Life Assessment
- PROCEDURE Biopsy
- OTHER Laboratory Biomarker Analysis
- DRUG Megestrol Acetate
- OTHER Pharmacological Study
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2007-07 |
| Phase | Phase 2 |
Why NCT00503581 stopped before completion
NCT00503581 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 5 interventions - of which Quality-of-Life Assessment is the first listed.
NCT00503581 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00503581 about?
NCT00503581 is a clinical study titled "Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia". This randomized phase II trial is studying how well megestrol works in treating patients with endometrial neoplasia or endometrial hyperplasia. Estrogen can cause the growth of endometrial cancer cells. Hormone therapy using megestrol may fight endometrial cancer by blocking the use of estrogen by t...
What is the current status of trial NCT00503581?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2007-07.
What interventions are being tested in trial NCT00503581?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Biopsy (PROCEDURE), Laboratory Biomarker Analysis (OTHER), Megestrol Acetate (DRUG), Pharmacological Study (OTHER).
Who is sponsoring clinical trial NCT00503581?
This trial is sponsored by Gynecologic Oncology Group, which has 154 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00503581's enrollment target sits among peer trials
9 1989th of 2000 higher than 11 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia