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NCT00500370 · ClinicalTrials.gov registry record · Phase 2

A Pilot Study of Effects of Exenatide on Body Weight in Non-Diabetic, Obese Patients

A Phase 2 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 2
Development phase
163
Enrollment target

NCT00500370: Completed Phase 2 study, sponsored by AstraZeneca.

NCT00500370 is a Phase 2 study that has completed, run by AstraZeneca. The registered enrollment target is 163 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00500370, a Phase 2 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 2
Development phase
163 participants
Enrollment target

Study Summary

This is a multicenter study designed to compare the effect of exenatide plus a lifestyle modification plan versus placebo plus a lifestyle modification plan on weight loss in non-diabetic, obese subjects.

Primary Outcome

Change in body weight from baseline after 24 weeks of treatment (i.e., body weight at week 24 minus body weight at week 0)

Interventions

  • DRUG placebo
  • DRUG exenatide

Trial Details

FieldValue
Enrollment Target 163 participants
Start Date 2007-06
Est. Completion 2008-02
Phase Phase 2
AstraZeneca

1,285 total trials

What the finished NCT00500370 record still lists

NCT00500370 is an interventional study that assigns participants to a tested intervention. The registered 163 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% higher).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT00500370 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00500370 about?

NCT00500370 is a clinical study titled "A Pilot Study of Effects of Exenatide on Body Weight in Non-Diabetic, Obese Patients". This is a multicenter study designed to compare the effect of exenatide plus a lifestyle modification plan versus placebo plus a lifestyle modification plan on weight loss in non-diabetic, obese subjects.

What is the current status of trial NCT00500370?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 163 participants. The study started on 2007-06. Estimated completion is 2008-02.

What interventions are being tested in trial NCT00500370?

The interventions under investigation include: placebo (DRUG), exenatide (DRUG).

Who is sponsoring clinical trial NCT00500370?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00500370's enrollment target sits among peer trials

163 418th of 2000 higher than 1,583 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00500370, the US trial registry maintained by the National Library of Medicine. NCT00500370 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.