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NCT00498901 · ClinicalTrials.gov registry record · Phase 2
Letrozole and Goserelin or Leuprolide in Treating Premenopausal Estrogen Receptor-Positive Patients With Stage IV Breast Cancer
A Phase 2 study, sponsored by University of Washington.
- Terminated
- Registry status
- Phase 2
- Development phase
- 1
- Enrollment target
NCT00498901: Clinical Trial Phase 2 study, sponsored by University of Washington.
NCT00498901 is a Phase 2 study that was terminated before completion, run by University of Washington. The registered enrollment target is 1 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00498901, a Phase 2 study, was terminated before completion, sponsored by University of Washington.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 1 participants
- Enrollment target
Study Summary
RATIONALE: Aromatase inhibitors, such as letrozole, prevent the formation of estradiol, a female hormone. Giving letrozole together with goserelin, leuprolide, or surgery may be an effective treatment in women with hormone-dependent breast cancer. PURPOSE: This phase II trial is studying how well giving letrozole together with goserelin or leuprolide works in treating premenopausal estrogen receptor-positive patients with stage IV breast cancer.
Interventions
- DRUG letrozole
- DRUG leuprolide acetate
- DRUG goserelin
- PROCEDURE conventional surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2007-02 |
| Est. Completion | 2008-11 |
| Phase | Phase 2 |
Why NCT00498901 stopped before completion
NCT00498901 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 4 interventions - of which letrozole is the first listed.
NCT00498901 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00498901 about?
NCT00498901 is a clinical study titled "Letrozole and Goserelin or Leuprolide in Treating Premenopausal Estrogen Receptor-Positive Patients With Stage IV Breast Cancer". RATIONALE: Aromatase inhibitors, such as letrozole, prevent the formation of estradiol, a female hormone. Giving letrozole together with goserelin, leuprolide, or surgery may be an effective treatment in women with hormone-dependent breast cancer. PURPOSE: This phase II trial is studying how well g...
What is the current status of trial NCT00498901?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2007-02. Estimated completion is 2008-11.
What interventions are being tested in trial NCT00498901?
The interventions under investigation include: letrozole (DRUG), leuprolide acetate (DRUG), goserelin (DRUG), conventional surgery (PROCEDURE).
Who is sponsoring clinical trial NCT00498901?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00498901's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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